1,3-Dichloro-2,5-difluorobenzene

Base Information

• Chemical Name: 1,3-Dichloro-2,5-difluorobenzene
• CAS No.: 2367-80-8
• Molecular Formula: C6H2Cl2F2
• Molecular Weight: 182.985
• Hs Code.: 2903999090
• DSSTox Substance ID: DTXSID00178339
• Wikidata: Q83048731
• Mol file: 2367-80-8.mol

Synonyms:1,3-dichloro-2,5-difluorobenzene;2367-80-8;1, 3-Dichloro-2,5-difluorobenzene;Benzene, 1,3-dichloro-2,5-difluoro-;1,3-Dichloro-2,5-difluoro-benzene;Benzene,1,3-dichloro-2,5-difluoro-;SCHEMBL7549121;DTXSID00178339;MFCD06658263;AKOS006346042;AC-9703;AM61856;DS-17616;CS-0157722;FT-0634227;A20570;A20830

Chemical Property of 1,3-Dichloro-2,5-difluorobenzene

Chemical Property:

• Vapor Pressure: 10.1mmHg at 25°C
• Melting Point: -10-3.5 °C
• Refractive Index: 1.478
• Boiling Point: 173.4 °C at 760 mmHg
• Flash Point: 60.4 °C
• PSA: 0.00000
• Density: 1.502 g/cm³
• LogP: 3.27160
• Storage Temp.: 2-8°C
• XLogP3: 3.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 181.9501618
• Heavy Atom Count: 10
• Complexity: 108

Purity/Quality:

98% ^*data from raw suppliers

1,3-Dichloro-2,5-difluorobenzene 95.0% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(C=C(C(=C1Cl)F)Cl)F

Technology Process of 1,3-Dichloro-2,5-difluorobenzene

There total 3 articles about 1,3-Dichloro-2,5-difluorobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.5%

2,5-difluoro-4,6-dichloroaniline (1314936-85-0) → 2,5-difluoro-1,3-dichlorobenzene (2367-80-8)

Guidance literature:

With isopentyl nitrite; In N,N-dimethyl-formamide; at 50 - 65 ℃;

Reference yield:

→ 2,5-difluoro-1,3-dichlorobenzene (2367-80-8)

Guidance literature:

DOI:10.1021/ja01145a055

Reference yield:

→ 2,5-difluoro-1,3-dichlorobenzene (2367-80-8)

Guidance literature:

2,4,6-Trichlorfluorbenzol, KF;

DOI:10.1016/S0022-1139(00)82962-0

upstream raw materials:

2,5-difluoro-4,6-dichloroaniline

Refernces