2,4-Dihydroxyisophthalaldehyde

Base Information

• Chemical Name: 2,4-Dihydroxyisophthalaldehyde
• CAS No.: 3328-71-0
• Molecular Formula: C8H6 O4
• Molecular Weight: 166.133
• Hs Code.: 2912499000
• DSSTox Substance ID: DTXSID40470006
• Mol file: 3328-71-0.mol

Synonyms:2,4-Dihydroxyisophthalaldehyde;3328-71-0;2,4-dihydroxybenzene-1,3-dicarbaldehyde;2,4-DIHYDROXY-BENZENE-1,3-DICARB-ALDEHYDE;SCHEMBL10748907;2,4-dihydroxyisophthalic aldehyde;DTXSID40470006;AKOS006288621;BS-51771;E78466

Chemical Property of 2,4-Dihydroxyisophthalaldehyde

Chemical Property:

• PSA: 74.60000
• LogP: 0.72280
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• XLogP3: 0.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 166.02660867
• Heavy Atom Count: 12
• Complexity: 180

Purity/Quality:

99%min ^*data from raw suppliers

2,4-Dihydroxyisophthalaldehyde 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C(=C1C=O)O)C=O)O

Technology Process of 2,4-Dihydroxyisophthalaldehyde

There total 10 articles about 2,4-Dihydroxyisophthalaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

1,3-dimethoxy-2,4-diformylbenzene (875902-97-9) → 2,4-dihydroxyisophthalic anhydride (3328-71-0)

Guidance literature:

With boron tribromide; In dichloromethane; at 0 - 20 ℃;

DOI:10.1021/jo052277t

Reference yield:

recorcinol (108-46-3) → 2,4-dihydroxyisophthalic anhydride (3328-71-0) + 2,4-Dihydroxybenzaldehyde (95-01-2)

Guidance literature:

With sodium hydroxide; chloroform;

Reference yield:

N,N'-diphenylformamidine (864131-95-3) + recorcinol (108-46-3) → 2,4-dihydroxyisophthalic anhydride (3328-71-0) + 2,4-Dihydroxybenzaldehyde (95-01-2)

Guidance literature:

at 130 ℃; und Hydrolyse des entstandenen 4.6-Dioxy-isophthalaldehyddianils mit sied.Natronlauge;

upstream raw materials:

N,N'-diphenylformamidine

recorcinol

chloroform

1-methyl-4-nitrosobenzene

Downstream raw materials:

2,4-dimethylbenzene-1,3-diol

1,2,3,4-tetrahydroxybenzene

5-bromo-2,4-dihydroxyisophthalaldehyde

acetic acid

Refernces