4-Hydroxy-2-phenylpyridine

Base Information

• Chemical Name: 4-Hydroxy-2-phenylpyridine
• CAS No.: 3262-40-6
• Molecular Formula: C11H9NO
• Molecular Weight: 171.199
• Hs Code.: 2933399090
• Mol file: 3262-40-6.mol

Synonyms:4-HYDROXY-2-PHENYLPYRIDINE

Chemical Property of 4-Hydroxy-2-phenylpyridine

Chemical Property:

• Vapor Pressure: 0.000137mmHg at 25°C
• Refractive Index: 1.594
• Boiling Point: 333.3 °C at 760 mmHg
• Flash Point: 150.3 °C
• PSA: 33.12000
• Density: 1.158 g/cm³
• LogP: 2.45420

Purity/Quality:

99% ^*data from raw suppliers

2-Phenyl-4-pyridone 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Hydroxy-2-phenylpyridine

There total 1 articles about 4-Hydroxy-2-phenylpyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 2-phenyl-1H-pyridin-4-one (3262-40-6)

Guidance literature:

Diketoaldehyd 3, NH3;

DOI:10.1021/ja01092a032

Reference yield: 95.0%

5-Chloro-1-phenyltetrazole (14210-25-4) + 2-phenyl-1H-pyridin-4-one (3262-40-6) → 2-phenyl-4-(1-phenyl-5-tetrazolyloxy)pyridine (126814-07-1)

Guidance literature:

With potassium carbonate; In acetonitrile; for 18h; Heating;

Reference yield:

2-phenyl-1H-pyridin-4-one (3262-40-6) → 2-phenylpyridine (1008-89-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / K₂CO₃ / acetonitrile / 18 h / Heating

2: 81 percent / ammonium formate / Pd/C / ethanol / 0.17 h / Heating

With ammonium formate; potassium carbonate; palladium on activated charcoal; In ethanol; acetonitrile;

Downstream raw materials:

2-phenyl-4-(1-phenyl-5-tetrazolyloxy)pyridine

2-phenylpyridine