(S)-1,2-Diphenylethylamine

Base Information

• Chemical Name: (S)-1,2-Diphenylethylamine
• CAS No.: 3082-58-4
• Molecular Formula: C14H15 N
• Molecular Weight: 197.28
• Mol file: 3082-58-4.mol

Synonyms:Benzeneethanamine,a-phenyl-, (S)-; Ethylamine,1,2-diphenyl-, (S)-(+)- (8CI); (+)-(S)-1,2-Diphenylethylamine; (+)-1,2-Diphenylethylamine;(+)-a,b-Diphenylethylamine; (S)-1,2-Diphenylethylamine; FPL12859; d-a-Benzylbenzylamine

Chemical Property of (S)-1,2-Diphenylethylamine

Chemical Property:

• Boiling Point: 115-120 °C(Press: 0.35 Torr)
• PKA: 8.78±0.10(Predicted)
• PSA: 26.02000
• Density: 1.052±0.06 g/cm3(Predicted)
• LogP: 3.62940

Purity/Quality:

99%min ^*data from raw suppliers

(1S)-1,2-Diphenylethan-1-amine >95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (S)-1,2-Diphenylethylamine

There total 40 articles about (S)-1,2-Diphenylethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

(1S)-1-phenyl-2-[(S)-2-(p-toluenesulfinyl)phenyl]ethylamine (503819-33-8) → (S)-1,2-diphenylethyl amine (3082-58-4)

Guidance literature:

nickel; In tetrahydrofuran;

DOI:10.1002/chem.200601893

Reference yield: 75.0%

C21H21NO → (S)-1,2-diphenylethyl amine (3082-58-4)

Guidance literature:

With ammonium cerium(IV) nitrate; In water; acetonitrile;

DOI:10.1002/chem.200601893

Reference yield: 73.0%

C21H21NOS → (S)-1,2-diphenylethyl amine (3082-58-4)

Guidance literature:

With nickel; In tetrahydrofuran; water; at 20 ℃;

DOI:10.1039/b816846f

upstream raw materials:

D_g-threo-α'-chloro-bibenzyl-α-ylamine

N'-(1,2-diphenylethylidene)benzohydrazide

(1S,4R)-2-[(E)-(R)-1,2-Diphenyl-ethylimino]-7,7-dimethyl-bicyclo[2.2.1]heptane-1-carboxylic acid (2-hydroxy-phenyl)-amide

3-benzyl-(4S)-isopropyl-1,3-oxazolidin-2-one

Downstream raw materials:

(1S,1'S)-(+)-N-(2'-hydroxy-1'-isopropylethyl)-1,2-diphenylethylamine

N-benzoyl-(-)-1,2-diphenylethylamine

(5R)-5-(4-imidazolylmethyl)-3-<(S)-1,2-diphenylethyl>-2,4-imidazolidinedione

(S)-(+)-1-(1,2-diphenylethyl)piperidine

Refernces

• 1、 Kim, Sol,Choi, Yoon Kyung,Hong, Jieun,Park, Jaiwook,Kim, Mahn-Joo. "Candida antarctica lipase A and Pseudomonas stutzeri lipase as a pair of stereocomplementary enzymes for the resolution of 1,2-diarylethanols and 1,2-diarylethanamines". supporting information. p. 1185 - 1188. Retrieved 2013/03/13.
• 2、 García Ruano, José Luis,Parra, Alejandro,Alemán, José,Yuste, Francisco,Mastranzo, Virginia M.. "Monoalkylation of primary amines and N-sulfinylamides". supporting information; scheme or table. p. 404 - 406. Retrieved 2009/05/06.