L-erythro-3-(3,4-Dihydroxyphenyl)serine

Base Information

• Chemical Name: L-erythro-3-(3,4-Dihydroxyphenyl)serine
• CAS No.: 34047-62-6
• Molecular Formula: C9H11 N O5
• Molecular Weight: 213.19
• Mol file: 34047-62-6.mol

Synonyms:L-Tyrosine,b,3-dihydroxy-, erythro-; Serine,3-(3,4-dihydroxyphenyl)-, L-erythro- (8CI);(+)-erythro-3,4-Dihydroxyphenylserine; L-erythro-3,4-Dihydroxyphenylserine;L-erythro-3-(3,4-Dihydroxyphenyl)serine; erythro-Dopaserine

Chemical Property of L-erythro-3-(3,4-Dihydroxyphenyl)serine

Chemical Property:

• Boiling Point: 549.8±50.0 °C(Predicted)
• PKA: 2.09±0.24(Predicted)
• PSA: 124.01000
• Density: 1.608±0.06 g/cm3(Predicted)
• LogP: 0.24340

Purity/Quality:

99% ^*data from raw suppliers

erythro-β,3-Dihydroxy-L-tyrosine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: erythro-β,3-Dihydroxy-L-tyrosine administered to rats inhibited the methamphetamins-induced locomotor activity and decreased the brain dopamine content.

Technology Process of L-erythro-3-(3,4-Dihydroxyphenyl)serine

There total 12 articles about L-erythro-3-(3,4-Dihydroxyphenyl)serine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.9%

DL-threo-N-carbobenzoxy-3-(3,4-dihydroxyphenyl)serine → L-threo-3-(3,4-dihydroxyphenyl)serine (34047-62-6)

Guidance literature:

With hydrogenchloride; palladium-carbon; In methanol; water;

Reference yield: 90.5%

→ 3-(3,4-dihydroxyphenyl)serine (492-46-6) + L-threo-3-(3,4-dihydroxyphenyl)serine (34047-62-6)

Guidance literature:

Reference yield: 80.5%

ascorbic acid (50-81-7,98966-42-8) → L-threo-3-(3,4-dihydroxyphenyl)serine (34047-62-6)

Guidance literature:

upstream raw materials:

D,L-threo-3-(3,4-Dibenzyloxyphenyl)serine

3,4-dibenzyloxybenzaldehyde

3,4-bis(ethoxycarboxy)-benzaldehyde

(2RS.3RS)-2-amino-3-(3,4-bis-benzyloxy-phenyl)-3-hydroxy-propionic acid

Refernces

• 1、 -. "Method for treatment of antidiuresis". . . Retrieved 2008/06/13.
• 2、 -. "Process for producing threo-3-(3,4-dihydroxyphenyl)serine". . . Retrieved 2008/06/13.