O-4-bromophenyl S-methyl dithiocarbonate

Base Information

• Chemical Name: O-4-bromophenyl S-methyl dithiocarbonate
• CAS No.: 143582-87-0
• Molecular Formula: C₈H₇BrOS₂
• Molecular Weight: 263.179
• Mol file: 143582-87-0.mol

Synonyms:O-4-bromophenyl S-methyl dithiocarbonate

Chemical Property of O-4-bromophenyl S-methyl dithiocarbonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of O-4-bromophenyl S-methyl dithiocarbonate

There total 2 articles about O-4-bromophenyl S-methyl dithiocarbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

4-bromo-phenol (106-41-2) + 3-methyl-1-(methyldithiocarbonyl)imidazolium iodide → O-4-bromophenyl S-methyl dithiocarbonate (143582-87-0)

Guidance literature:

With triethylamine; In acetonitrile; at 0 ℃; for 1h; Inert atmosphere;

DOI:10.1021/acs.joc.9b02717

Reference yield: 67.0%

carbon disulfide (75-15-0,12122-00-8) + 4-bromo-phenol (106-41-2) + methyl iodide (74-88-4) → O-4-bromophenyl S-methyl dithiocarbonate (143582-87-0)

Guidance literature:

carbon disulfide; 4-bromo-phenol; With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 10h;

methyl iodide; In N,N-dimethyl-formamide; at 20 ℃; for 1h;

DOI:10.1246/bcsj.73.471

Reference yield: 68.0%

O-4-bromophenyl S-methyl dithiocarbonate (143582-87-0) → 1-bromo-4-[difluoro(methylthio)methoxy]benzene (143582-98-3)

Guidance literature:

With iodine pentafluoride-pyridine-hydrogen fluoride; In dichloromethane; at 20 ℃; for 24h;

DOI:10.1016/j.jfluchem.2015.04.016

upstream raw materials:

carbon disulfide

4-bromo-phenol

methyl iodide

Downstream raw materials:

1-bromo-4-(trifluoromethoxy)benzene

1-bromo-4-[difluoro(methylthio)methoxy]benzene

Refernces

• 1、 Inoue, Toshiya,Fuse, Chiaki,Hara, Shoji. "Synthesis of trifluoromethyl ethers and difluoro(methylthio)methyl ethers by the reaction of dithiocarbonates with IF5-pyridine-HF". . p. 48 - 52. Retrieved 2015/11/10.