1-iodo-2-(trimethylsilyl)benzene

Base Information

• Chemical Name: 1-iodo-2-(trimethylsilyl)benzene
• CAS No.: 22424-65-3
• Molecular Formula: C₉H₁₃ISi
• Molecular Weight: 276.192
• Mol file: 22424-65-3.mol

Synonyms:1-iodo-2-(trimethylsilyl)benzene

Chemical Property of 1-iodo-2-(trimethylsilyl)benzene

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 1-iodo-2-(trimethylsilyl)benzene

There total 5 articles about 1-iodo-2-(trimethylsilyl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

1,2-bis(trimethylsilyl)benzene (17151-09-6) → 1-iodo-2-(trimethylsilyl)benzene (22424-65-3)

Guidance literature:

With N-iodo-succinimide; In acetic acid; at 20 ℃; for 2h;

DOI:10.1055/s-0036-1588726

Reference yield:

2,3-dibromobenzene (583-53-9) → 1-iodo-2-(trimethylsilyl)benzene (22424-65-3)

Guidance literature:

Multi-step reaction with 2 steps

1: magnesium / tetrahydrofuran / Inert atmosphere

2: Iodine monochloride; pyridine / dichloromethane / Inert atmosphere

With pyridine; Iodine monochloride; magnesium; In tetrahydrofuran; dichloromethane;

DOI:10.1039/c6dt04293g

Reference yield:

1,2-dichloro-benzene (95-50-1) → 1-iodo-2-(trimethylsilyl)benzene (22424-65-3)

Guidance literature:

Multi-step reaction with 2 steps

1: magnesium; lithium chloride / 17 h / 90 °C

2: N-iodo-succinimide / acetic acid / 2 h / 20 °C

With N-iodo-succinimide; magnesium; lithium chloride; In acetic acid;

DOI:10.1055/s-0036-1588726

upstream raw materials:

1,2-bis(trimethylsilyl)benzene

(2-chloro-phenyl)-trimethyl-silane

2,3-dibromobenzene

1,2-dichloro-benzene

Downstream raw materials:

tris(o-trimethylsilylphenyl)silane

tris(o-iodophenyl)silane

Refernces

• 1、 Tomaschautzky, Janek,Neumann, Beate,Stammler, Hans-Georg,Mix, Andreas,Mitzel, Norbert W.. "Tridentate Lewis-acids based on triphenylsilane". . p. 1645 - 1659. Retrieved 2017/02/10.