(Methoxymethyl)triphenylphosphonium bromide

Base Information

• Chemical Name: (Methoxymethyl)triphenylphosphonium bromide
• CAS No.: 33670-32-5
• Molecular Formula: C20H20 O P . Br
• Molecular Weight: 387.256
• Hs Code.: 2931900090
• European Community (EC) Number: 687-307-9
• DSSTox Substance ID: DTXSID60378616
• Mol file: 33670-32-5.mol

Synonyms:(Methoxymethyl)triphenylphosphonium bromide;33670-32-5;methoxymethyl(triphenyl)phosphanium;bromide;MFCD00075442;C20H20BrOP;Methoxymethyl)triphenylphosphonium bromide;(methoxymethyl)triphenylphosphanium bromide;Phosphonium, (methoxymethyl)triphenyl-, bromide;PHOSPHAZENEBASEP1-T-BU;SCHEMBL595357;DTXSID60378616;NOCGROPYCGRERZ-UHFFFAOYSA-M;AMY42188;AKOS005256325;CS-W006206;methoxymethyltriphenylphosphonium bromide;methoxymethyl triphenylphosphonium bromide;SY287427;(methoxymethyl) triphenylphosphonium bromide;(Methoxymethyl)tris(phenyl)phosphonium bromide;A850237

Chemical Property of (Methoxymethyl)triphenylphosphonium bromide

Chemical Property:

• Melting Point: 175-179 °C
• PSA: 22.82000
• LogP: 0.58840
• Storage Temp.: Inert atmosphere,Room Temperature
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 386.04351
• Heavy Atom Count: 23
• Complexity: 266

Purity/Quality:

98% ^*data from raw suppliers

(Methoxymethyl)tris(phenyl)phosphonium bromide ^*data from reagent suppliers

Safty Information:

• Hazard Codes: C,Xi
• Statements: 14-34-37
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC[P+](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3.[Br-]

Technology Process of (Methoxymethyl)triphenylphosphonium bromide

There total 2 articles about (Methoxymethyl)triphenylphosphonium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.7%

bromethyl methyl ether (13057-17-5) + triphenylphosphine (603-35-0) → methoxymethyltriphenylphosphonium bromide (33670-32-5)

Guidance literature:

In benzene; for 24h; Ambient temperature;

DOI:10.1246/bcsj.53.3436

Reference yield:

→ methoxymethyltriphenylphosphonium bromide (33670-32-5)

Guidance literature:

Reference yield: 93.0%

2-chloro-4-(4-chlorophenoxy)benzaldehyde + methoxymethyltriphenylphosphonium bromide (33670-32-5) → (E)-2-chloro-4-(4-chlorophenoxy)-1-(2-methoxyvinyl)benzene (1614262-44-0)

Guidance literature:

methoxymethyltriphenylphosphonium bromide; With lithium hexamethyldisilazane; In tetrahydrofuran; at 0 ℃; for 1h;

2-chloro-4-(4-chlorophenoxy)benzaldehyde; In tetrahydrofuran;

upstream raw materials:

bromethyl methyl ether

triphenylphosphine

Downstream raw materials:

-cyclopropan

-cyclobutan

3-[1-Methoxy-meth-(Z)-ylidene]-1-methyl-cyclohexanecarbonitrile

(E)-1-(Phenylsulfonyl)-3-(β-methoxyvinyl)indole

Refernces

• 1、 Frydrych, Ivo,Urban, Milan,?arek, Jan,Benická, Sandra,D?ubák, Petr,Gurská, Soňa,Hajdúch, Marián,Kotulová, Jana,Li?ková, Barbora,Olejníková, Denisa,Pokorny, Jan. "Substituted dienes prepared from betulinic acid – Synthesis, cytotoxicity, mechanism of action, and pharmacological parameters". . . Retrieved 2021/07/28.
• 2、 -. "4-PHENYLPIPERIDINE DERIVATIVES AS RENIN INHIBITORS". Page/Page column 69. . Retrieved 2008/06/13.