Technology Process of L-glycero-L-gluco-Heptitol, 2,6-anhydro-4-azido-4-deoxy-1,3:5,7-bis-O-(phenylmethylene)-
There total 11 articles about L-glycero-L-gluco-Heptitol, 2,6-anhydro-4-azido-4-deoxy-1,3:5,7-bis-O-(phenylmethylene)- which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 8 steps
1: NaH2PO2 / Raney nickel
2: p-toluenesulfonic acid monohydrate / CH2Cl2; acetone / 0.33 h
3: sodium borohydride / methanol / 0.33 h
4: 287 mg / pyridine
5: 85 percent / sodium methoxide; methanol / 20 h
6: TsOH
7: 73 percent / 4-(dimethylamino)pyridine; pyridine / 3 h / 70 °C
8: 10 percent / sodium azide / dimethylsulfoxide / 1 h / 180 °C
With
pyridine; methanol; dmap; sodium tetrahydroborate; sodium hypophosphite; sodium azide; sodium methylate; toluene-4-sulfonic acid;
nickel;
In
methanol; dichloromethane; dimethyl sulfoxide; acetone;
1: Reduction / 2: Hydrolysis / 3: Reduction / 4: Acetylation / 5: Deacetylation / 6: acetalization / 7: Tosylation / 8: Substitution;
DOI:10.1016/S0040-4020(99)00327-0
- Guidance literature:
-
Multi-step reaction with 3 steps
1: TsOH
2: 73 percent / 4-(dimethylamino)pyridine; pyridine / 3 h / 70 °C
3: 10 percent / sodium azide / dimethylsulfoxide / 1 h / 180 °C
With
pyridine; dmap; sodium azide; toluene-4-sulfonic acid;
In
dimethyl sulfoxide;
1: acetalization / 2: Tosylation / 3: Substitution;
DOI:10.1016/S0040-4020(99)00327-0