3,4-Difluorophenylglycine

Base Information

• Chemical Name: 3,4-Difluorophenylglycine
• CAS No.: 225641-94-1
• Molecular Formula: C₈H₇F₂NO₂
• Molecular Weight: 187.146
• Hs Code.: 2922499990
• Mol file: 225641-94-1.mol

Synonyms:3,4-Difluorophenylglycine;amino(3,4-difluorophenyl)acetic acid;2-Amino-2-(3,4-difluorophenyl)acetic acid;3,4-Difluoro-DL-phenylglycine;3,4-Difluorophenylglycine;Amino(3,4-difluorophenyl)acetic acid;

Chemical Property of 3,4-Difluorophenylglycine

Chemical Property:

• Vapor Pressure: 0.00104mmHg at 25°C
• Refractive Index: 1.543
• Boiling Point: 289 °C at 760 mmHg
• PKA: 1.70±0.10(Predicted)
• Flash Point: 128.6 °C
• PSA: 63.32000
• Density: 1.442 g/cm³
• LogP: 1.74950

Purity/Quality:

98%min ^*data from raw suppliers

3,4-Difluorophenylglycine 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,4-Difluorophenylglycine

There total 1 articles about 3,4-Difluorophenylglycine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

amino-(3,4-difluorophenyl)-acetonitrile (218449-30-0) → DL-(3,4-difluorophenyl)glycine (225641-94-1)

Guidance literature:

With sulfuric acid; at 90 ℃; for 17h;

DOI:10.1016/j.bmcl.2009.04.016

Reference yield:

trifluoroacetic anhydride (407-25-0) + DL-(3,4-difluorophenyl)glycine (225641-94-1) → C10H4F5NO2

Guidance literature:

at 20 ℃; Neat (no solvent);

DOI:10.1016/j.bmc.2009.10.055

upstream raw materials:

amino-(3,4-difluorophenyl)-acetonitrile

Refernces