2-aminophenylboronic acid (+)-pinanediol ester

Base Information

• Chemical Name: 2-aminophenylboronic acid (+)-pinanediol ester
• CAS No.: 616227-06-6
• Molecular Formula: C₁₆H₂₂BNO₂
• Molecular Weight: 271.167
• Mol file: 616227-06-6.mol

Synonyms:2-aminophenylboronic acid (+)-pinanediol ester

Chemical Property of 2-aminophenylboronic acid (+)-pinanediol ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-aminophenylboronic acid (+)-pinanediol ester

There total 4 articles about 2-aminophenylboronic acid (+)-pinanediol ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

pinanediol (18680-27-8) + 2-aminophenylboronic acid (5570-18-3) → 2-aminophenylboronic acid (+)-pinanediol ester (616227-06-6)

Guidance literature:

In tetrahydrofuran;

DOI:10.1016/S0022-328X(03)00400-5

Reference yield:

2-nitrophenylboronic acid (5570-19-4) → 2-aminophenylboronic acid (+)-pinanediol ester (616227-06-6)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂ / Pd/C / ethanol

2: 89 percent / tetrahydrofuran

With hydrogen; palladium on activated charcoal; In tetrahydrofuran; ethanol;

DOI:10.1016/S0022-328X(03)00400-5

Reference yield:

phenylboronic acid (98-80-6) → 2-aminophenylboronic acid (+)-pinanediol ester (616227-06-6)

Guidance literature:

Multi-step reaction with 3 steps

1: HNO₃; Ac₂O; urea

2: H₂ / Pd/C / ethanol

3: tetrahydrofuran

With hydrogen; nitric acid; acetic anhydride; urea; palladium on activated charcoal; In tetrahydrofuran; ethanol;

DOI:10.1055/s-2002-20470

upstream raw materials:

pinanediol

2-aminophenylboronic acid

2-nitrophenylboronic acid

phenylboronic acid

Refernces

• 1、 Kennedy, Jason W. J.,Hall, Dennis G.. "Self-activation and 1,8-stereoinduction in a boronate-substituted dienophile". . p. 477 - 479. Retrieved 2007/10/03.