4-Isothiocyanatobenzoyl Azide

Base Information

• Chemical Name: 4-Isothiocyanatobenzoyl Azide
• CAS No.: 78889-15-3
• Molecular Formula: C₈H₄N₄OS
• Molecular Weight: 204.212
• Mol file: 78889-15-3.mol

Synonyms:4-Isothiocyanatobenzoyl Azide

Chemical Property of 4-Isothiocyanatobenzoyl Azide

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

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Technology Process of 4-Isothiocyanatobenzoyl Azide

There total 2 articles about 4-Isothiocyanatobenzoyl Azide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-isothiocyanatobenzoic acid (2131-62-6) → 4-Isothiocyanatobenzoyl Azide (78889-15-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 41 g / SOCl₂ / 3 h / Heating

2: 34 g / NaN₃ / H₂O; acetone / 1.) 5 deg C , 30 min , 2.) RT , 1 h

With thionyl chloride; sodium azide; In water; acetone;

Reference yield:

4-isothiocyanato benzoyl chloride (53611-24-8) → 4-Isothiocyanatobenzoyl Azide (78889-15-3)

Guidance literature:

With sodium azide; In water; acetone; 1.) 5 deg C , 30 min , 2.) RT , 1 h;

Reference yield:

4-Isothiocyanatobenzoyl Azide (78889-15-3) → Amoscanate (26328-53-0,100990-46-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 3.6 g / toluene / 4 h / Heating

2: 6.7 g / Pyridine / benzene / 3 h / 50 - 60 °C

3: 0.1 g / anhydrous K₂CO₃ / nitrobenzene / 3 h / 190 °C / Further catalysts

With pyridine; potassium carbonate; In nitrobenzene; toluene; benzene;

upstream raw materials:

4-isothiocyanato benzoyl chloride

4-isothiocyanatobenzoic acid

Downstream raw materials:

p-Isothiocyanatophenyl isocyanate

(4-Isothiocyanato-phenyl)-carbamic acid 4-nitro-phenyl ester

Amoscanate

Refernces

• 1、 Viswanathan, N.,Desai, Ranjit C.. "A new Synthesis of 4-Isothiocyanato-4'-nitrodiphenylamine (Amoscanate)". . p. 308 - 310. Retrieved 2007/10/02.