2-phenyl-2-(trichloromethyl)-3-chlorooxirane

Base Information

• Chemical Name: 2-phenyl-2-(trichloromethyl)-3-chlorooxirane
• CAS No.: 97295-21-1
• Molecular Formula: C₉H₆Cl₄O
• Molecular Weight: 271.958
• Mol file: 97295-21-1.mol

Synonyms:2-phenyl-2-(trichloromethyl)-3-chlorooxirane

Chemical Property of 2-phenyl-2-(trichloromethyl)-3-chlorooxirane

Chemical Property:

Purity/Quality:

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Technology Process of 2-phenyl-2-(trichloromethyl)-3-chlorooxirane

There total 3 articles about 2-phenyl-2-(trichloromethyl)-3-chlorooxirane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

2,2-dichloroacetophenone (2648-61-5) + sodium trichloroacetate (650-51-1) → 2-phenyl-2-(trichloromethyl)-3-chlorooxirane (97295-21-1)

Guidance literature:

In chloroform; for 6h; Heating;

DOI:10.1021/jo00220a010

Reference yield: 46.0%

tetrachloromethane (56-23-5) + acetophenone (98-86-2) → benzoic acid (65-85-0,8013-63-6) + 2-phenyl-2-(trichloromethyl)oxirane (75590-20-4) + 2-phenyl-2-(trichloromethyl)-3-chlorooxirane (97295-21-1)

Guidance literature:

With sodium hydroxide; tetrabutylammomium bromide; for 4h; Product distribution; other arylalkyl ketones and reaction time;

DOI:10.1021/jo00220a010

Reference yield: 15.0%

tetrachloromethane (56-23-5) + acetophenone (98-86-2) → 2-phenyl-2-(trichloromethyl)-3-chlorooxirane (97295-21-1)

Guidance literature:

With sodium hydroxide; tetrabutylammomium bromide; for 4h; Ambient temperature;

DOI:10.1021/jo00220a010

upstream raw materials:

2,2-dichloroacetophenone

sodium trichloroacetate

tetrachloromethane

acetophenone

Refernces