4,4'-Dihydroxybenzil

Base Information

• Chemical Name: 4,4'-Dihydroxybenzil
• CAS No.: 33288-79-8
• Molecular Formula: C14H10 O4
• Molecular Weight: 242.231
• Hs Code.: 2914501900
• Mol file: 33288-79-8.mol

Synonyms:Benzil,4,4'-dihydroxy- (6CI,7CI,8CI); Ethanedione, bis(4-hydroxyphenyl)- (9CI);4,4'-Dihydroxybenzil

Chemical Property of 4,4'-Dihydroxybenzil

Chemical Property:

• Vapor Pressure: 1.22E-10mmHg at 25°C
• Melting Point: 235 °C(Solv: water (7732-18-5))
• Refractive Index: 1.654
• Boiling Point: 500.4°C at 760 mmHg
• PKA: 6.02±0.15(Predicted)
• Flash Point: 270.6°C
• PSA: 74.60000
• Density: 1.366g/cm³
• LogP: 2.16340
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

1,2-Bis(4-hydroxyphenyl)ethane-1,2-dione 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4,4'-Dihydroxybenzil

There total 10 articles about 4,4'-Dihydroxybenzil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1,2-bis(4-methoxyphenyl)-1,2-ethanedione (1226-42-2) → 4,4'-dihydroxybenzil (33288-79-8)

Guidance literature:

With pyridine hydrochloride; at 220 ℃; for 1.5h;

DOI:10.1021/ol060025o

Reference yield: 85.0%

4,4'-dimethoxybenzoin (119-52-8) → 4,4'-dihydroxybenzil (33288-79-8)

Guidance literature:

With calcium hydride; diphenyldisulfane; In 1-methyl-pyrrolidin-2-one; for 0.5h; Inert atmosphere; Reflux;

DOI:10.1039/c7tc00173h

Reference yield: 28.0%

1,2-bis(4-methoxyphenyl)-1,2-ethanedione (1226-42-2) → 4-hydroxy-4'-methoxybenzil (54945-19-6) + 4,4'-dihydroxybenzil (33288-79-8)

Guidance literature:

With hydrogen bromide; In water; acetic acid; for 17h; Reflux;

DOI:10.1039/b9nj00519f

upstream raw materials:

1,2-bis(4-methoxyphenyl)-1,2-ethanedione

4,4'-dimethoxybenzoin

4-methoxy-benzaldehyde

1,4-di(4-methoxyphenyl)ethanone

Downstream raw materials:

3-[4,5-bis-(4-hydroxy-phenyl)-1H-imidazol-2-yl]-4-hydroxy-chromen-2-one

racemic di(4-oxyphenyl-2',2'-dimethyl-1',3'-dioxacyclopentyl-4'-methyl)ethanedione-1,2

4.4'-Dihydroxy-benzil-dihydrazon

1,2-bis-(4-{2-[2-(2-{2-[2-(4-iodo-phenoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-phenyl)-ethane-1,2-dione

Refernces

• 1、 Giansante, Carlo,Ceroni, Paola,Balzani, Vincenzo,Maestri, Mauro,Lee, Sang-Kyu,Voegtle, Fritz. "Photophysical, photochemical, and electrochemical properties of dendrimers with a dimethoxybenzil core". . p. 1250 - 1258. Retrieved 2007.
• 2、 Zhang, Yan,Du, Hongmei,Yin, Yiming,Dong, Yunyun,Zhao, Jinsheng,Xu, Zhen. "Synthesis and characterization of soluble donor-acceptor type copolymers based on benzotriazole, quinoxaline and benzene units with multicolor electrochromism". . . Retrieved 2019/11/11.