1,2:5,6-DI-O-CYCLOHEXYLIDENE-MYO-INOSITOL

Base Information

• Chemical Name: 1,2:5,6-DI-O-CYCLOHEXYLIDENE-MYO-INOSITOL
• CAS No.: 33021-17-9
• Molecular Formula: C18H28 O6
• Molecular Weight: 340.413
• Mol file: 33021-17-9.mol

Synonyms:Inositol,1,2:5,6-di-O-cyclohexylidene-, D-myo- (8CI);Dispiro[cyclohexane-1,2'-benzo[1,2-d:3,4-d']bis[1,3]dioxole-7',1''-cyclohexane],D-myo-inositol deriv.

Chemical Property of 1,2:5,6-DI-O-CYCLOHEXYLIDENE-MYO-INOSITOL

Chemical Property:

• PSA: 77.38000
• LogP: 1.61060

Purity/Quality:

99% ^*data from raw suppliers

1,2:5,6-DI-O-CYCLOHEXYLIDENE-MYO-INOSITOL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,2:5,6-DI-O-CYCLOHEXYLIDENE-MYO-INOSITOL

There total 29 articles about 1,2:5,6-DI-O-CYCLOHEXYLIDENE-MYO-INOSITOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

1-O-butyryl-2,3:4,5-di-O-cyclohexylidene-myo-inositol (889659-13-6) → (-)-2,3:4,5-di-O-cyclohexylidene-myo-inositol (33021-17-9)

Guidance literature:

With porcine pancreatic lipase; In diethyl ether; hexane; at 37 ℃; for 168h; pH=~ 7; Aqueous phosphate buffer;

Reference yield: 40.0%

cycloxexanone dimethyl ketal (933-40-4) + D-myo-inositol (87-89-8) → (±)-1,2:4,5-di-O-cyclohexylidene-myo-inositol + (+/-)-1,2:5,6-dicyclohexylidene-myo-inositol (6763-49-1,23393-19-3,33021-17-9,34361-61-0,34395-04-5,34711-26-7,40773-57-7,41545-19-1,54712-58-2,57089-24-4,57089-25-5,68738-25-0,81601-23-2,120710-65-8,141506-87-8) + (±)-1,2:3,4-di-O-cyclohexylidene-myo-inositol (6763-49-1,23393-19-3,33021-17-9,34361-61-0,34395-04-5,34711-26-7,40773-57-7,41545-19-1,54712-58-2,57089-24-4,57089-25-5,68738-25-0,81601-23-2,120710-65-8,141506-87-8)

Guidance literature:

With H₂SO₄ supported on silica; In N,N-dimethyl-formamide; at 60 ℃; for 0.75h; under 300.03 Torr; Inert atmosphere; Green chemistry;

DOI:10.1039/c3ra40506k

Reference yield: 40.0%

cycloxexanone dimethyl ketal (933-40-4) + D-myo-inositol (87-89-8) → (±)-1,2:4,5-di-O-cyclohexylidene-myo-inositol + (+/-)-1,2:5,6-dicyclohexylidene-myo-inositol (6763-49-1,23393-19-3,33021-17-9,34361-61-0,34395-04-5,34711-26-7,40773-57-7,41545-19-1,54712-58-2,57089-24-4,57089-25-5,68738-25-0,81601-23-2,120710-65-8,141506-87-8) + (±)-1,2:3,4-di-O-cyclohexylidene-myo-inositol (6763-49-1,23393-19-3,33021-17-9,34361-61-0,34395-04-5,34711-26-7,40773-57-7,41545-19-1,54712-58-2,57089-24-4,57089-25-5,68738-25-0,81601-23-2,120710-65-8,141506-87-8)

Guidance literature:

With H₂SO₄ supported on silica; In N,N-dimethyl-formamide; at 60 ℃; for 0.75h; under 300.03 Torr; Inert atmosphere; Green chemistry;

DOI:10.1039/c3ra40506k

upstream raw materials:

D-myo-inositol

1-ethoxycyclohexene

1,6-Di-O-acetyl-2,3:4,5-di-O-cyclohexylidene-D/L-myo-inositol

D-3-acetyl-1,2:5,6-di-O-cyclohexylidene-myo-inositol

Downstream raw materials:

(-)-3,4-di-O-benzyl-1,2-O-cyclohexylidene-myo-inositol

(-)-6-O-allyl-3,4,5-tri-O-benzyl-myo-inositol

C₃₆H₄₂O₆

1D-6-O-allyl-3,4,5-tri-O-benzyl-1-O-(4-methoxybenzoyl)-myo-inositol

Refernces

• 1、 Vibhute, Amol M.,Sureshan, Kana M.. "H2SO4-silica: An eco-friendly heterogeneous catalyst for the differential protection of myo-inositol hydroxyl groups". . p. 7321 - 7329. Retrieved 2013/07/05.
• 2、 -. "Inositol-phosphate derivatives and method of detecting inositol-1-phosphate". Page/Page column 38. . Retrieved 2012/05/20.