Penoxsulam

Base Information

• Chemical Name: Penoxsulam
• CAS No.: 219714-96-2
• Molecular Formula: C₁₆H₁₄F₅N₅O₅S
• Molecular Weight: 483.376
• Mol file: 219714-96-2.mol

Synonyms:DASH 001;Granite;Penoxsulam;Ricer 240SC;

Chemical Property of Penoxsulam

Chemical Property:

• Melting Point: 223-224°
• Refractive Index: 1.588
• PKA: 5.1(at 25℃)
• PSA: 125.32000
• Density: 1.65g/cm³
• LogP: 3.75880
• Storage Temp.: 0-6°C

Purity/Quality:

95.0%, ^*data from raw suppliers

Penoxsulam ^*data from reagent suppliers

Safty Information:

• Pictogram(s): N
• Hazard Codes: N
• Statements: 50/53
• Safety Statements: 61

MSDS Files:

SDS file from LookChem

Useful:

• Description: Penoxsulam, developed and produced by Dow AgroSciences LLC (Dow AgroSciences), is a trizolo pyrimidine herbicide applied in paddy fields with the widest herbicidal spectrum. It has great effect not only in aquatic weeds control but also in barnyard grass which has resistance to herbicides like quinclorac, propanil and sulfonylurea. With aquatic weeds’ higher resistance, penoxsulam plays a more vital part in weeds control. Penoxsulam is an acetolactate synthase inhibitor herbicide. It provides broad-spectrum control of many annual, biannual, and perennial weeds. It is used mainly as a post-emergency foliar spray or a granular formulation for the control of broadleaf, sedge, and grass weeds in transplanted, dryseeded, and water-seeded rice. It is also effective against broadleaf weeds in corn, sorghum, wheat, barley and other cereal crops, lawns, golf courses, parks, cemeteries, athletic fields, sod farms, tree and vine crops, range and pasture, roadsides, and other crop and non-crop uses. As penoxsulam does not bind strongly to either soil or sediments, it tends to be very mobile in both aqueous and terrestrial environments, which makes it a contaminant to groundwater. Penoxsulam is registered for use in Germany, France, Portugal and the USA.
• Uses: Penxosulam is a triazolo-pyrimidine sulfonamide herbicide, which is used to control the growth of annual grasses, sedges, and broadleaf weeds in rice agriculture. The compound inhibits the synthesis of acetolactate and targets the biosynthesis of branch-chained amino acids, a metabolic pathway found in plants, fungi, and microorganisms. Acetolactate synthase (ALS) inhibitors are present in most effective herbicides. They are used in agriculture because they show a broad weed control spectrum, crop selectivity, are safe to humans, and can be applied at relatively low usage rates. Herbicide.

Technology Process of Penoxsulam

There total 19 articles about Penoxsulam which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2-fluoro-6-trifluoromethyl-N-(5,8-dimethoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)benzenesulfonamide (219713-41-4) + difluoroethanol (359-13-7) → penoxsulam (219714-96-2)

Guidance literature:

With sodium; In 1,2-dimethoxyethane; at 5 - 25 ℃; for 3h; Reagent/catalyst; Temperature; Inert atmosphere;

Reference yield: 91.7%

2-amino-5,8-dimethoxy[1,2,4]triazolo-[1,5-c]pyrimidine (219715-62-5) + C9H6F6O3S → penoxsulam (219714-96-2)

Guidance literature:

With dmap; In N,N-dimethyl-formamide; at 60 ℃; for 6h; Reagent/catalyst;

Reference yield: 91.0%

2-amino-5,8-dimethoxy[1,2,4]triazolo-[1,5-c]pyrimidine (219715-62-5) + 2-(2',2'-difluoroethoxy)-6-trifluoromethylbenzene-1-sulfonyl chloride (865352-01-8) → penoxsulam (219714-96-2)

Guidance literature:

With 3,5-Lutidine; dimethyl sulfoxide; In 3,5-Lutidine; at 20 ℃; for 8.5h; Product distribution / selectivity;

upstream raw materials:

2-amino-5,8-dimethoxy[1,2,4]triazolo-[1,5-c]pyrimidine

2-(2',2'-difluoroethoxy)-6-trifluoromethylbenzene-1-sulfonyl chloride

2-fluoro-6-trifluoromethyl-N-(5,8-dimethoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)benzenesulfonamide

difluoroethanol

Refernces

• 1、 -. "Improved [...] synthetic method". Paragraph 0054-0063. . Retrieved 2019/05/08.
• 2、 -. "2 - phenoxy four hydrogens fu ([...]) five fluorine sulphur grass amine[...] derivatives and their application in the synthesis of". Paragraph 0111; 0112; 0113; 0114. . Retrieved 2017/06/30.