3-Methoxy-2-furfuraldehyde

Base Information

• Chemical Name: 3-Methoxy-2-furfuraldehyde
• CAS No.: 32487-58-4
• Molecular Formula: C6H6 O3
• Molecular Weight: 126.112
• Mol file: 32487-58-4.mol

Synonyms:2-Furaldehyde,3-methoxy- (8CI)

Chemical Property of 3-Methoxy-2-furfuraldehyde

Chemical Property:

• Boiling Point: 229.2±20.0 °C(Predicted)
• PSA: 39.44000
• Density: 1.168±0.06 g/cm3(Predicted)
• LogP: 1.10070
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

3-Methoxyfuran-2-carbaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Methoxy-2-furfuraldehyde

There total 3 articles about 3-Methoxy-2-furfuraldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

3-bromofurfural (14757-78-9) + sodium methylate (124-41-4) → 3-methoxyfuran-2-carbaldehyde (32487-58-4)

Guidance literature:

In methanol; at 20 - 64 ℃; for 18h; Inert atmosphere; Reflux;

DOI:10.1055/s-0031-1290103

Reference yield: 55.0%

furan-3-methanol (3420-57-3) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → 3-methoxyfuran-2-carbaldehyde (32487-58-4)

Guidance literature:

N,N-dimethyl-formamide; With oxalyl dichloride; In dichloromethane; at 0 ℃; for 0.6h;

furan-3-methanol; In dichloromethane; at -40 ℃; for 0.333333h; Further stages.;

DOI:10.1021/ol071377d

Reference yield:

→ 3-methoxyfuran-2-carbaldehyde (32487-58-4)

Guidance literature:

1) 3-Brom-furfural-diethylacetal, NaOCH3, CuO; 2) H⁺, H2O;

upstream raw materials:

furan-3-methanol

N,N-dimethyl-formamide

3-bromofurfural

sodium methylate

Refernces

• 1、 -. "SYNTHESIS OF ENONE INTERMEDIATE". Page/Page column 86-87. . Retrieved 2008/12/08.