4-DIMETHYLAMINO-2,2,6,6-TETRAMETHYLPIPERIDINE

Base Information

• Chemical Name: 4-DIMETHYLAMINO-2,2,6,6-TETRAMETHYLPIPERIDINE
• CAS No.: 32327-90-5
• Molecular Formula: C11H24 N2
• Molecular Weight: 184.32
• Hs Code.: 2933399090
• Mol file: 32327-90-5.mol

Synonyms:Piperidine,4-(dimethylamino)-2,2,6,6-tetramethyl- (8CI);4-(Dimethylamino)-2,2,6,6-tetramethylpiperidine

Chemical Property of 4-DIMETHYLAMINO-2,2,6,6-TETRAMETHYLPIPERIDINE

Chemical Property:

• Vapor Pressure: 0.164mmHg at 25°C
• Refractive Index: n20/D 1.4641(lit.)
• Boiling Point: 213.5°C at 760 mmHg
• PKA: 10.83±0.10(Predicted)
• Flash Point: 120 °F
• PSA: 15.27000
• Density: 0.88g/cm³
• LogP: 2.18600

Purity/Quality:

99.9% ^*data from raw suppliers

4-Dimethylamino-2,2,6,6-tetramethylpiperidine 96% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 10-36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: Reactant for: Self-aggregation of supramolecules of nitroxides Synthesis of unsymmetrical spin-labeled bolaamphiphiles

Technology Process of 4-DIMETHYLAMINO-2,2,6,6-TETRAMETHYLPIPERIDINE

There total 4 articles about 4-DIMETHYLAMINO-2,2,6,6-TETRAMETHYLPIPERIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.3%

2,2,6,6-Tetramethyl-4-piperidone (826-36-8) + dimethyl amine (124-40-3) → 4-dimethylamino-2,2,6,6-tetramethyl piperidine (32327-90-5)

Guidance literature:

With formic acid; In 5,5-dimethyl-1,3-cyclohexadiene; at 130 - 135 ℃; for 5h; Inert atmosphere;

Reference yield: 85.9%

4-AMINO-2,2,6,6-TETRAMETHYLPIPERIDINE (36768-62-4) + formaldehyd (50-00-0,30525-89-4,61233-19-0) → 4-dimethylamino-2,2,6,6-tetramethyl piperidine (32327-90-5)

Guidance literature:

With formic acid; In water; Cooling with ice;

Reference yield: 58.3%

4-AMINO-2,2,6,6-TETRAMETHYLPIPERIDINE (36768-62-4) + formaldehyd (50-00-0,30525-89-4,61233-19-0) → 4-dimethylamino-2,2,6,6-tetramethyl piperidine (32327-90-5) + 4-(Dimethylamino)-1,2,2,6,6-pentamethylpiperidine (36177-86-3)

Guidance literature:

With palladium on activated charcoal; hydrogen; In methanol; water; at 80 - 140 ℃; under 15001.5 - 31503.2 Torr; Autoclave;

upstream raw materials:

4-AMINO-2,2,6,6-TETRAMETHYLPIPERIDINE

formaldehyd

2,2,6,6-Tetramethyl-4-piperidone

dimethyl amine

Downstream raw materials:

Br^(1-)*C₅₃H₈₉N₄O₇⁽¹⁺⁾

4-trimethylammonium-2,2,6,6-tetramethyl-piperidine-1-oxyl

Refernces

• 1、 Kornberg,McConnell. "Inside-outside transitions of phospholipids in vesicle membranes.". . p. 1111 - 1120. Retrieved 1971.
• 2、 -. "Hindered phenol-containing hindered amine light stabilizer, and preparation method and application thereof". Paragraph 0054-0056. . Retrieved 2020/12/14.
• 3、 -. "MATERIALS FOR USE IN AN AQUEOUS ORGANIC REDOX FLOW BATTERY". Paragraph 0311; 0312. . Retrieved 2018/05/15.