N-<4-nitro-1-(benzoyloxy)-3-benzyl>-1,2-dioleoylphosphatidylcholine

Base Information

• Chemical Name: N-<4-nitro-1-(benzoyloxy)-3-benzyl>-1,2-dioleoylphosphatidylcholine
• CAS No.: 138630-87-2
• Molecular Formula: C₅₇H₉₁N₂O₁₂P
• Molecular Weight: 1027.33
• Mol file: 138630-87-2.mol

Synonyms:N-<4-nitro-1-(benzoyloxy)-3-benzyl>-1,2-dioleoylphosphatidylcholine

Chemical Property of N-<4-nitro-1-(benzoyloxy)-3-benzyl>-1,2-dioleoylphosphatidylcholine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-<4-nitro-1-(benzoyloxy)-3-benzyl>-1,2-dioleoylphosphatidylcholine

There total 2 articles about N-<4-nitro-1-(benzoyloxy)-3-benzyl>-1,2-dioleoylphosphatidylcholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

dioleoylphosphatidylcholine (68737-67-7) → N-<4-nitro-1-(benzoyloxy)-3-benzyl>-1,2-dioleoylphosphatidylcholine (138630-87-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 67 percent / 80 mM CaCl₂ / diethyl ether / 44 h / 30 °C / 200 mM sodium acetate buffer, phospholipase D

2: 1.) tetrabutylammonium hydroxide / 1.) CHCl₃, CH₃OH, 2.) CHCl₃, RT, 18 h

With tetra(n-butyl)ammonium hydroxide; calcium chloride; In diethyl ether;

DOI:10.1021/ja00031a033

Reference yield:

4-Nitro-3-(bromomethyl)phenyl benzoate (120411-98-5) + N,N-dimethyl-1,2-dioleoylphosphatidylethanolamine (87803-75-6,96647-99-3,96687-22-8) → N-<4-nitro-1-(benzoyloxy)-3-benzyl>-1,2-dioleoylphosphatidylcholine (138630-87-2)

Guidance literature:

With tetra(n-butyl)ammonium hydroxide; Yield given. Multistep reaction; 1.) CHCl₃, CH₃OH, 2.) CHCl₃, RT, 18 h;

DOI:10.1021/ja00031a033

Reference yield:

N-<4-nitro-1-(benzoyloxy)-3-benzyl>-1,2-dioleoylphosphatidylcholine (138630-87-2) → C50H87N2O11P + benzoic acid (65-85-0,8013-63-6)

Guidance literature:

With sodium hydroxide; BIS-TRIS; potassium chloride; at 25 ℃; Rate constant; other liposome; saponification of endovesicular and exovesicular groups;

DOI:10.1021/ja00031a033

upstream raw materials:

4-Nitro-3-(bromomethyl)phenyl benzoate

N,N-dimethyl-1,2-dioleoylphosphatidylethanolamine

dioleoylphosphatidylcholine

Downstream raw materials:

benzoic acid

Refernces