Deoxyfuconojirimycin (hydrochloride)

Base Information

• Chemical Name: Deoxyfuconojirimycin (hydrochloride)
• CAS No.: 210174-73-5
• Molecular Formula: C₆H₁₃NO₃*ClH
• Molecular Weight: 183.635
• Hs Code.: 2933998090
• European Community (EC) Number: 640-216-8
• Mol file: 210174-73-5.mol

Synonyms:210174-73-5;2-methylpiperidine-3,4,5-triol;hydrochloride;Deoxyfuconojirimycin, Hydrochloride;1,5-Dideoxy-1,5-imino-L-fucitol hydrochloride;Deoxyfuconojirimycin (hydrochloride);FT-0665816

Chemical Property of Deoxyfuconojirimycin (hydrochloride)

Chemical Property:

• Melting Point: 155-157°C
• Storage Temp.: Refrigerator, Under Inert Atmosphere
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 183.0662210
• Heavy Atom Count: 11
• Complexity: 120

Purity/Quality:

95% ^*data from raw suppliers

Deoxyfuconojirimycin hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1C(C(C(CN1)O)O)O.Cl
• Uses: A powerful and specific inhibitor of several alpha-L-fucosidases.

Technology Process of Deoxyfuconojirimycin (hydrochloride)

There total 23 articles about Deoxyfuconojirimycin (hydrochloride) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

N-benzyloxycarbonyl-1,5,6-trideoxy-1,5-imino-D-glucitol (910222-14-9) → 1,5,6-trideoxy-1,5-imino-D-glucitol hydrochloride (210174-73-5)

Guidance literature:

With hydrogenchloride; hydrogen; palladium dihydroxide; In methanol; water; for 6h; under 3051.17 Torr; pH=3 - 4;

DOI:10.1016/j.carres.2006.06.002

Reference yield:

2-O-benzyl-N-benzyl-1,5,6-trideoxy-1,5-imino-L-altritol → 1,5,6-trideoxy-1,5-imino-L-altritol hydrochloride (210174-73-5)

Guidance literature:

With hydrogenchloride; palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 24h; pH=2;

DOI:10.1016/j.carres.2019.107744

Reference yield:

2-O-benzyl-N-benzyl-1,5,6-trideoxy-1,5-imino-D-galactitol → 1,6-dideoxy-D-galactostatin hydrochloride (210174-73-5)

Guidance literature:

With hydrogenchloride; palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 24h; pH=2;

DOI:10.1016/j.carres.2019.107744

upstream raw materials:

6-Deoxy-1,2-O-isopropylidene-D-mannono-γ-lactam

2,3-O-isopropylidene-L-gulono-γ-lactone

6-Deoxy-2,3-O-isopropylidene-L-gulono-γ-lactone

6-Bromo-6-deoxy-2,3-O-isopropylidene-L-gulono-γ-lactone

Refernces

• 1、 An, Jia-Ning,Meng, Xiang-Bao,Yao, Yun,Li, Zhong-Jun. "A facile synthesis of 1,6-dideoxynojirimycin from l-sorbose". . p. 2200 - 2203. Retrieved 2007/10/03.