C₄₄H₄₅NO₁₄

Base Information

• Chemical Name: C₄₄H₄₅NO₁₄
• CAS No.: 145260-75-9
• Molecular Formula: C₄₄H₄₅NO₁₄
• Molecular Weight: 811.84
• Mol file: 145260-75-9.mol

Synonyms:C₄₄H₄₅NO₁₄

Chemical Property of C₄₄H₄₅NO₁₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₄H₄₅NO₁₄

There total 7 articles about C₄₄H₄₅NO₁₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

C44H43NO14 (145260-84-0) → C44H45NO14 (145260-75-9)

Guidance literature:

With hydrogenchloride; sodium cyanoborohydride; In methanol; Ambient temperature;

DOI:10.1039/c39920001494

Reference yield:

methyl 4-O-benzoyl-6-bromo-6-deoxy-α-D-glucopyranoside (10368-81-7) → C44H45NO14 (145260-75-9)

Guidance literature:

Multi-step reaction with 7 steps

1: 1.) Raney Ni, H₂, 2.) Et₃N / 1.) MeOH, 2.) AcOEt

2: 82 percent / CSA / dimethylformamide / 60 °C

3: 80 percent / MeONa / methanol / Ambient temperature

4: PCC, molecular sieves 4 A, AcONa / CH₂Cl₂

5: NH₂OH, HCl, pyridine / ethanol / 60 °C

6: 95 percent / Tf₂O / 1.5 h / -78 - -35 °C

7: 98 percent / NaCNBH₃, HCl / methanol / Ambient temperature

With pyridine; hydrogenchloride; trifluoromethylsulfonic anhydride; 4 A molecular sieve; camphor-10-sulfonic acid; hydrogen; hydroxylamine; sodium methylate; sodium acetate; nickel; sodium cyanoborohydride; triethylamine; pyridinium chlorochromate; In methanol; ethanol; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1039/c39920001494

Reference yield:

methyl 4-O-benzoyl-6-deoxy-α-D-glucopyranoside (79774-54-2) → C44H45NO14 (145260-75-9)

Guidance literature:

Multi-step reaction with 6 steps

1: 82 percent / CSA / dimethylformamide / 60 °C

2: 80 percent / MeONa / methanol / Ambient temperature

3: PCC, molecular sieves 4 A, AcONa / CH₂Cl₂

4: NH₂OH, HCl, pyridine / ethanol / 60 °C

5: 95 percent / Tf₂O / 1.5 h / -78 - -35 °C

6: 98 percent / NaCNBH₃, HCl / methanol / Ambient temperature

With pyridine; hydrogenchloride; trifluoromethylsulfonic anhydride; 4 A molecular sieve; camphor-10-sulfonic acid; hydroxylamine; sodium methylate; sodium acetate; sodium cyanoborohydride; pyridinium chlorochromate; In methanol; ethanol; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1039/c39920001494

upstream raw materials:

C₄₄H₄₃NO₁₄

methyl 4-O-benzoyl-6-bromo-6-deoxy-α-D-glucopyranoside

methyl 4-O-benzoyl-6-deoxy-α-D-glucopyranoside

(3aR,4S,6R,7aS)-4-Methoxy-2,2,6-trimethyl-dihydro-[1,3]dioxolo[4,5-c]pyran-7-one oxime

Downstream raw materials:

C₄₉H₄₇NO₁₅

Refernces