3alpha-Methoxy-21beta-hydroxy-delta13-serratene

Base Information

• Chemical Name: 3alpha-Methoxy-21beta-hydroxy-delta13-serratene
• CAS No.: 24433-34-9
• Molecular Formula: C₃₁H₅₂O₂
• Molecular Weight: 456.753
• Mol file: 24433-34-9.mol

Synonyms:C(14a)-Homo-27-norgammacer-13-en-21-ol,3-methoxy-, (3a,21b)-;C(14a)-Homo-27-norgammacer-13-en-21b-ol, 3a-methoxy- (8CI)

Chemical Property of 3alpha-Methoxy-21beta-hydroxy-delta13-serratene

Chemical Property:

• Boiling Point: 521.4±50.0 °C(Predicted)
• PKA: 15.17±0.70(Predicted)
• PSA: 29.46000
• Density: 1.03±0.1 g/cm3(Predicted)
• LogP: 7.93790

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3alpha-Methoxy-21beta-hydroxy-delta13-serratene

There total 6 articles about 3alpha-Methoxy-21beta-hydroxy-delta13-serratene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3α-methoxyserrat-13-en-21β-yl acetate → 3α-Methoxy-21β-hydroxy-serrat-13-en (24433-34-9)

Guidance literature:

With potassium hydroxide; In methanol; for 8h;

DOI:10.1016/j.ejmech.2011.04.062

Reference yield:

3α-methoxyserrat-14-en-21β-ol acetate → 3α-Methoxy-21β-hydroxy-serrat-13-en (24433-34-9)

Guidance literature:

Multistep reaction; (i) H₂SO₄, AcOH, (ii) LiAlH₄;

DOI:10.1016/S0040-4020(01)82906-9

Reference yield:

3α-methoxyserrat-14-en-21β-ol → 3α-Methoxy-21β-hydroxy-serrat-13-en (24433-34-9)

Guidance literature:

Multi-step reaction with 3 steps

1: pyridine

2: sulfuric acid; acetic acid / 24 h / 20 °C

3: potassium hydroxide / methanol / 8 h

With pyridine; sulfuric acid; acetic acid; potassium hydroxide; In methanol;

DOI:10.1016/j.ejmech.2011.04.062

upstream raw materials:

3β-methoxyserrat-13-en-21β-yl acetate

Refernces

• 1、 Tanaka, Reiko,Tsujii, Hiroko,Yamada, Takeshi,Kajimoto, Tetsuya,Tokuda, Harukuni,Arai, Takanari,Suzuki, Nobutaka,Hasegawa, Junya,Hamashima, Yoshio,Node, Manabu. "Conjugates of 3α-methoxyserrat-14-en-21β-ol (PJ-1) and 3β-methoxyserrat-14-en-21β-ol (PJ-2) as cancer chemopreventive agents". . p. 3368 - 3375. Retrieved 2011/07/29.
• 2、 Kutney,Rogers. "The neutral triterpenes of the bark of Picea sitchensis (Sitka spruce).". . p. 3731 - 3751. Retrieved 2007/10/10.