Methyl Perfluoroamyl Ketone

Base Information

• Chemical Name: Methyl Perfluoroamyl Ketone
• CAS No.: 2708-07-8
• Molecular Formula: C7H3 F11 O
• Molecular Weight: 312.08
• Hs Code.: 2914700090
• European Community (EC) Number: 678-337-3
• DSSTox Substance ID: DTXSID00578936
• Nikkaji Number: J1.843.259E
• Wikidata: Q81986086
• Mol file: 2708-07-8.mol

Synonyms:Methyl Perfluoroamyl Ketone;2708-07-8;1H,1H,1H-Undecafluoro-2-heptanone;Methyl Perfluoropentyl Ketone;Methyl Undecafluoroamyl Ketone;3,3,4,4,5,5,6,6,7,7,7-Undecafluoroheptan-2-one;1H,1H,1H-Perfluoroheptan-2-one;5:2 ketone;Methyl perfluoro-n-amyl ketone;SCHEMBL2124333;Methyl Undecafluoropentyl Ketone;3,3,4,4,5,5,6,6,7,7,7-Undecafluoro-2-heptanone;DTXSID00578936;HWGNOHFZECDUBX-UHFFFAOYSA-N;MFCD02093506;AKOS015852641;NS00018721;U0071;T72203;J-016670

Chemical Property of Methyl Perfluoroamyl Ketone

Chemical Property:

• Vapor Pressure: 28.9mmHg at 25°C
• Refractive Index: 1.286
• Boiling Point: 105.9°C at 760 mmHg
• Flash Point: 31.8°C
• PSA: 17.07000
• Density: 1.60
• LogP: 3.67890
• XLogP3: 3.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 12
• Rotatable Bond Count: 4
• Exact Mass: 312.00082450
• Heavy Atom Count: 19
• Complexity: 366

Purity/Quality:

98%,99%, ^*data from raw suppliers

1H,1H,1H-Perfluoroheptan-2-one ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)C(C(C(C(C(F)(F)F)(F)F)(F)F)(F)F)(F)F

Technology Process of Methyl Perfluoroamyl Ketone

There total 1 articles about Methyl Perfluoroamyl Ketone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

undecafluorohexanoic acid (307-24-4) + methylmagnesium bromide (75-16-1) → 3,3,4,4,5,5,6,6,7,7,7-undecafluoroheptan-2-one (2708-07-8)

Guidance literature:

undecafluorohexanoic acid; methylmagnesium bromide; In diethyl ether; at -8 - 20 ℃; for 2h; Inert atmosphere;

With hydrogenchloride; In water;

DOI:10.1021/ol301766w

Reference yield:

3,3,4,4,5,5,6,6,7,7,7-undecafluoroheptan-2-one (2708-07-8) → C21H15F11O

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 0.5 h / 0 °C / Inert atmosphere

2: gallium(III) trichloride / dichloromethane / 20 °C / Inert atmosphere

With gallium(III) trichloride; triethylamine; In dichloromethane;

DOI:10.1021/ol301766w

Reference yield:

3,3,4,4,5,5,6,6,7,7,7-undecafluoroheptan-2-one (2708-07-8) → 4,4,5,5,6,6,7,7,8,8,8-undecafluoro-1,1-diphenyloctan-3-one (1391912-52-9)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 0.5 h / 0 °C / Inert atmosphere

2: gallium(III) trichloride / dichloromethane / 0.17 h / -78 °C / Inert atmosphere

With gallium(III) trichloride; triethylamine; In dichloromethane;

DOI:10.1021/ol301766w

upstream raw materials:

undecafluorohexanoic acid

methylmagnesium bromide

Downstream raw materials:

4,4,5,5,6,6,7,7,8,8,8-undecafluoro-1,1-diphenyloctan-3-one

Refernces