METHYL 10-HYDROXYDECANOATE

Base Information

• Chemical Name: METHYL 10-HYDROXYDECANOATE
• CAS No.: 2640-94-0
• Molecular Formula: C11H22 O3
• Molecular Weight: 202.294
• Mol file: 2640-94-0.mol

Synonyms:Methyl10-hydroxydecanoate

Chemical Property of METHYL 10-HYDROXYDECANOATE

Chemical Property:

• Vapor Pressure: 0.000584mmHg at 25°C
• Refractive Index: n20/D 1.448(lit.)
• Boiling Point: 276.8°C at 760 mmHg
• PKA: 15.19±0.10(Predicted)
• Flash Point: 221 °F
• PSA: 46.53000
• Density: 0.962 g/mL at 25 °C(lit.)
• LogP: 2.27250

Purity/Quality:

98%,99%, ^*data from raw suppliers

Methyl 10-hydroxydecanoate technical grade, ≥90% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of METHYL 10-HYDROXYDECANOATE

There total 4 articles about METHYL 10-HYDROXYDECANOATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

sebacic acid mono methyl ester (818-88-2) → 1,10-Decanediol (112-47-0) + methyl 10-hydroxydecanoate (2640-94-0)

Guidance literature:

With water; Rh₆(CO)16*Mo(CO)6; In 1,2-dimethoxyethane; at 160 ℃; for 16h; under 76000 Torr;

DOI:10.1016/0040-4039(94)02453-I

Reference yield: 48.0%

methanol (67-56-1) + 1,10-Decanediol (112-47-0) → methyl 10-hydroxydecanoate (2640-94-0) + dimethyl sebacate (106-79-6)

Guidance literature:

With (2-hydroxyethyl)(methyl)amine; potassium phosphate; bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; In acetone; at 25 ℃; for 24h; Inert atmosphere;

DOI:10.1021/jo2003264

Reference yield:

Methyl decanoate (110-42-9) → methyl 10-hydroxydecanoate (2640-94-0) + 10-oxo-decanoic acid methyl ester (14811-73-5)

Guidance literature:

With oxygen; D-glucose; at 30 ℃; pH=7.4; aq. phosphate buffer; Enzymatic reaction;

DOI:10.1002/adsc.201100440

upstream raw materials:

Methyl 10-undecenoate

sebacic acid mono methyl ester

methanol

1,10-Decanediol

Downstream raw materials:

10-[4-((2R,3R,4S,5R,6S)-3,4,5-Tris-benzyloxy-6-methoxy-tetrahydro-pyran-2-ylmethoxysulfonyl)-phenoxy]-decanoic acid methyl ester

10-oxo-decanoic acid methyl ester

10-chlorodecanoic acid

10-fluorodecanoic acid

Refernces

• 1、 Schrewe, Manfred,Magnusson, Anders O.,Willrodt, Christian,Buehler, Bruno,Schmid, Andreas. "Kinetic analysis of terminal and unactivated C-H bond oxyfunctionalization in fatty acid methyl esters by monooxygenase-based whole-cell biocatalysis". experimental part. p. 3485 - 3495. Retrieved 2012/03/26.
• 2、 Flippin, Lee A.,Gallagher, David W.,Jalali-Araghi, Keyvan. "A Convenient Method for the Reduction of Ozonides to Alcohols with Borane-Dimethyl Sulfide Complex". . p. 1430 - 1432. Retrieved 2007/10/02.