Technology Process of 2-methyl-6-(1-phenylethyl)benzaldehyde
There total 5 articles about 2-methyl-6-(1-phenylethyl)benzaldehyde which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride; water;
In
ethyl acetate;
at 20 ℃;
for 0.5h;
Reagent/catalyst;
Temperature;
Inert atmosphere;
DOI:10.1002/anie.201207958
- Guidance literature:
-
With
hydrogenchloride; water;
In
tetrahydrofuran;
at 20 ℃;
for 1h;
Inert atmosphere;
DOI:10.1002/adsc.201600403
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: Tri(p-tolyl)phosphine; (trimethylsilyl)methylmagnesium chloride; cobalt(II) bromide / tetrahydrofuran / 0.5 h / Inert atmosphere; Schlenk technique; Cooling with ice
1.2: 12 h / 40 °C / Inert atmosphere; Schlenk technique
2.1: water; hydrogenchloride / ethyl acetate / 0.5 h / 20 °C / Inert atmosphere
With
hydrogenchloride; (trimethylsilyl)methylmagnesium chloride; water; Tri(p-tolyl)phosphine; cobalt(II) bromide;
In
tetrahydrofuran; ethyl acetate;
DOI:10.1002/anie.201207958
