(E)-3-Cyclohexyl-2-propen-1-ol

Base Information

• Chemical Name: (E)-3-Cyclohexyl-2-propen-1-ol
• CAS No.: 114096-03-6
• Molecular Formula: C₉H₁₆O
• Molecular Weight: 140.225
• Mol file: 114096-03-6.mol

Synonyms:2-Propen-1-ol,3-cyclohexyl-, (E)-;(2E)-3-Cyclohexylprop-2-en-1-ol;(E)-3-Cyclohexyl-2-propen-1-ol;(E)-3-Cyclohexylprop-2-enol;

Chemical Property of (E)-3-Cyclohexyl-2-propen-1-ol

Chemical Property:

• Vapor Pressure: 0.022mmHg at 25°C
• Refractive Index: 1.556
• Boiling Point: 221.482 °C at 760 mmHg
• Flash Point: 97.517 °C
• PSA: 20.23000
• Density: 1.003 g/cm³
• LogP: 2.11520

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (E)-3-Cyclohexyl-2-propen-1-ol

There total 35 articles about (E)-3-Cyclohexyl-2-propen-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methyl (2E)-3-cyclohexylprop-2-enoate (26429-99-2) → (E)-3-cyclohexyl-2-propen-1-ol (42134-55-4,132350-24-4,114096-03-6)

Guidance literature:

With diisobutylaluminium hydride; In dichloromethane; at -78 ℃; Inert atmosphere;

DOI:10.1021/ja105161f

Reference yield: 99.0%

(E)-3-cyclohexyl-acrylic acid ethyl ester (17343-88-3) → (E)-3-cyclohexyl-2-propen-1-ol (42134-55-4,132350-24-4,114096-03-6)

Guidance literature:

With diisobutylaluminium hydride; In hexane; dichloromethane; at -78 ℃; for 1h;

DOI:10.1016/S0040-4020(96)00934-9

Reference yield: 94.0%

3-cyclohexyl-2-propyn-1-ol (42134-54-3) → (E)-3-cyclohexyl-2-propen-1-ol (42134-55-4,132350-24-4,114096-03-6)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 18h; Ambient temperature;

DOI:10.1016/S0040-4020(01)90391-6

upstream raw materials:

trimethylsilyloxirane

phenyl hexyl sulfone

cyclohexylmagnesiumchloride

2-(1-chloro-2-propenyl)-1,3,2-dioxaborinane

Downstream raw materials:

(E)-1-Phenyl-4-cyclohexyl-but-3-en-1-ol

syn-3-cyclohexyl-4-hydroxy-4-phenyl-1-butene

anti-1-phenyl-2-cyclohexylbut-3-en-1-ol

(E)-4-Cyclohexyl-1-phenyl-but-3-en-1-ol

Refernces

• 1、 Morgan, Jeremy B.,Morken, James P.. "Platinum-catalyzed tandem diboration/asymmetric allylboration: Access to nonracemic functionalized 1,3-diols". . p. 2573 - 2575. Retrieved 2003.
• 2、 Huang, Jiaxin,Li, Jie,Yang, Wen,Zhang, Kezhuo,Zhao, Pei,Zhao, Wanxiang. "Ligand-controlled cobalt-catalyzed remote hydroboration and alkene isomerization of allylic siloxanes". supporting information. p. 302 - 305. Retrieved 2022/01/03.
• 3、 Gao, Peng-Chao,Li, Bi-Jie,Wang, Zi-Xuan. "Iridium-Catalyzed Regioselective Hydroalkynylation of Internal Alkenes Directed by an Oxime". supporting information. p. 9500 - 9504. Retrieved 2021/12/14.