C₅₅H₅₈ClN₁₀O₁₄P

Base Information

• Chemical Name: C₅₅H₅₈ClN₁₀O₁₄P
• CAS No.: 68892-36-4
• Molecular Formula: C₅₅H₅₈ClN₁₀O₁₄P
• Molecular Weight: 1149.55
• Mol file: 68892-36-4.mol

Synonyms:C₅₅H₅₈ClN₁₀O₁₄P

Chemical Property of C₅₅H₅₈ClN₁₀O₁₄P

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of C₅₅H₅₈ClN₁₀O₁₄P

There total 3 articles about C₅₅H₅₈ClN₁₀O₁₄P which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5'-O-dimethoxytrityl-N-isobutyryldeoxyguanosine (68892-41-1) → C55H58ClN10O14P (68892-36-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) pyridine, 2.) 5percent aq. NH₄HCO₃ / 1.) dioxane, 30 min at room temp.; 2.) dioxane, cooling

2: 1-(mesitylsulfonyl)tetrazole / pyridine / 1 h / Ambient temperature

With pyridine; 1-mesitylsulfonyl-1H-tetrazole; ammonium bicarbonate; In pyridine;

Reference yield:

(p-chlorophenyl) di(1,2,4-triazolido)phosphate (62420-37-5) → C55H58ClN10O14P (68892-36-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) pyridine, 2.) 5percent aq. NH₄HCO₃ / 1.) dioxane, 30 min at room temp.; 2.) dioxane, cooling

2: 1-(mesitylsulfonyl)tetrazole / pyridine / 1 h / Ambient temperature

With pyridine; 1-mesitylsulfonyl-1H-tetrazole; ammonium bicarbonate; In pyridine;

Reference yield:

N-isobutyryl-2'-deoxyguanosine (68892-42-2) + C41H40ClN5O10P(1-) (71100-63-5) → C55H58ClN10O14P (68892-36-4)

Guidance literature:

With 1-mesitylsulfonyl-1H-tetrazole; In pyridine; for 1h; Ambient temperature;

upstream raw materials:

N-isobutyryl-2'-deoxyguanosine

C₄₁H₄₀ClN₅O₁₀P^(1-)

5'-O-dimethoxytrityl-N-isobutyryldeoxyguanosine

(p-chlorophenyl) di(1,2,4-triazolido)phosphate

Downstream raw materials:

C₆₄H₆₅Cl₂N₁₁O₁₇P₂

C₄₃H₄₇Cl₂N₁₁O₁₅P₂

Refernces