meso-1,2-bis-(2-Bromophenyl)ethane-1,2-diamine

Base Information

• Chemical Name: meso-1,2-bis-(2-Bromophenyl)ethane-1,2-diamine
• CAS No.: 1057134-65-2
• Molecular Formula: C₁₄H₁₄Br₂N₂
• Molecular Weight: 370.087
• Mol file: 1057134-65-2.mol

Synonyms:meso-1,2-bis-(2-Bromophenyl)ethane-1,2-diamine

Chemical Property of meso-1,2-bis-(2-Bromophenyl)ethane-1,2-diamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of meso-1,2-bis-(2-Bromophenyl)ethane-1,2-diamine

There total 3 articles about meso-1,2-bis-(2-Bromophenyl)ethane-1,2-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C28H20Br4N2O → meso-1,2-bis-(2-Bromophenyl)ethane-1,2-diamine (1057134-65-2)

Guidance literature:

C₂₈H₂₀Br₄N₂O; With sulfuric acid; water; at 130 ℃;

With ammonia; In water;

Reference yield:

[1-(2-Bromo-phenyl)-meth-(E)-ylidene]-trimethylsilanyl-amine → meso-1,2-bis-(2-Bromophenyl)ethane-1,2-diamine (1057134-65-2) + (1S,2S)-1,2-Bis-(2-bromo-phenyl)-ethane-1,2-diamine

Guidance literature:

With potassium hydroxide; tetrachlorobis(tetrahydrofuran)niobium(IV); Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts; 1.) dimethoxyethane, 4 h, 2.) water;

DOI:10.1021/ja00244a052

Reference yield:

ortho-bromobenzaldehyde (6630-33-7) → meso-1,2-bis-(2-Bromophenyl)ethane-1,2-diamine (1057134-65-2)

Guidance literature:

Multi-step reaction with 2 steps

1: ammonium acetate / 130 °C

2: sulfuric acid; water / 130 °C

With sulfuric acid; ammonium acetate; water;

upstream raw materials:

ortho-bromobenzaldehyde

Refernces

• 1、 -. "Heterocyclic compounds as P2X7 ion channel blockers". Page/Page column 25. . Retrieved 2010/02/10.