Technology Process of spiro(2,7-bis[4-methoxyphenyl]fluorene-9,9'-fluorene)
There total 9 articles about spiro(2,7-bis[4-methoxyphenyl]fluorene-9,9'-fluorene) which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetrakis(triphenylphosphine) palladium(0); sodium carbonate;
In
water; toluene;
for 24h;
Inert atmosphere;
Reflux;
DOI:10.1021/ma102093t
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: chromium(VI) oxide; acetic acid / 1 h / 120 °C
2.1: iodine; magnesium / tetrahydrofuran / 2 h / Inert atmosphere; Reflux
2.2: 20 °C / Inert atmosphere; Reflux
3.1: hydrogenchloride; acetic acid / water / 2.5 h / 140 °C
4.1: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / water; toluene / 24 h / Inert atmosphere; Reflux
With
chromium(VI) oxide; hydrogenchloride; tetrakis(triphenylphosphine) palladium(0); iodine; sodium carbonate; magnesium; acetic acid;
In
tetrahydrofuran; water; toluene;
2.1: Grignard reaction / 2.2: Grignard reaction / 4.1: Suzuki coupling;
DOI:10.1021/ma102093t
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: 5% Pd(II)/C(eggshell); hydrogen / ethyl acetate / 24 h / 20 °C / 3800.26 Torr
2.1: hydrogenchloride; sodium nitrite / water / 0.25 h / 0 °C
2.2: 0 - 20 °C
3.1: iodine; magnesium / tetrahydrofuran / 2 h / Inert atmosphere; Reflux
3.2: 20 °C / Inert atmosphere; Reflux
4.1: hydrogenchloride; acetic acid / water / 2.5 h / 140 °C
5.1: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / water; toluene / 24 h / Inert atmosphere; Reflux
With
hydrogenchloride; tetrakis(triphenylphosphine) palladium(0); 5% Pd(II)/C(eggshell); hydrogen; iodine; sodium carbonate; magnesium; acetic acid; sodium nitrite;
In
tetrahydrofuran; water; ethyl acetate; toluene;
3.1: Grignard reaction / 3.2: Grignard reaction / 5.1: Suzuki coupling;
DOI:10.1021/ma102093t