(1S)-1-C-1H-benzimidazol-2-ylhexitol

Base Information

• Chemical Name: (1S)-1-C-1H-benzimidazol-2-ylhexitol
• CAS No.: 6631-58-9
• Molecular Formula: C₁₃H₁₈N₂O₆
• Molecular Weight: 298.296
• Mol file: 6631-58-9.mol

Synonyms:NSC 56091

Chemical Property of (1S)-1-C-1H-benzimidazol-2-ylhexitol

Chemical Property:

• Vapor Pressure: 2.55E-26mmHg at 25°C
• Boiling Point: 790.2°C at 760 mmHg
• Flash Point: 431.7°C
• Density: 1.645g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (1S)-1-C-1H-benzimidazol-2-ylhexitol

There total 8 articles about (1S)-1-C-1H-benzimidazol-2-ylhexitol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

D-glycero-L-gluco-heptonic acid (87-74-1,488-36-8,2782-86-7,20246-36-0,20246-58-6,23351-51-1,25520-99-4,35784-84-0,35784-85-1,70095-54-4,92470-58-1,136599-01-4) + 1,2-diamino-benzene (95-54-5) → D-(1R)-1-(1H-benzimidazol-2-yl)-galactitol (6631-58-9,6631-60-3,7596-30-7,20188-65-2,47167-80-6,51030-48-9)

Guidance literature:

With hydrogenchloride; at 135 ℃;

DOI:10.1021/ja01154a129

Reference yield:

D-glycero-D-gluco-heptonic acid-(N'-phenyl-hydrazide) (1194815-23-0) → (1S)-1-(1H-benzimidazol-2-yl)-D-altritol (6631-58-9,6631-60-3,7596-30-7,20188-65-2,47167-80-6,51030-48-9)

Guidance literature:

With water; copper(II) sulfate; Erhitzen des Reaktionsprodukts mit o-Phenylendiamin in wss. HCl unter Zusatz von H₃PO₄;

DOI:10.1021/ja01154a129

Reference yield:

D-altrose (1990-29-0) → (1S)-1-(1H-benzimidazol-2-yl)-D-altritol (6631-58-9,6631-60-3,7596-30-7,20188-65-2,47167-80-6,51030-48-9)

Guidance literature:

Multi-step reaction with 3 steps

1: water; aqueous ammonia / beim Erwaermen der Reaktionsloesung mit Bariumhydroxid;

3: CuSO₄; H₂O / Erhitzen des Reaktionsprodukts mit o-Phenylendiamin in wss. HCl unter Zusatz von H₃PO₄

With ammonium hydroxide; water; copper(II) sulfate;

DOI:10.1021/ja01154a129

upstream raw materials:

1,2-diamino-benzene

D-glycero-D-manno-heptonic acid-4-lactone

D-glycero-D-gluco-heptonic acid-(N'-phenyl-hydrazide)

D-altrose