Multi-step reaction with 10 steps
1.1: pyridine / dichloromethane / 5 h / 0 - 20 °C
2.1: perchloric acid / 1.5 h / 0 - 20 °C
3.1: platinum on activated charcoal; hydrogen / ethanol / 3 h / 20 °C
4.1: acetic acid / 0.5 h / 20 °C
4.2: 2 h / 20 °C
5.1: potassium carbonate; tetrakis(triphenylphosphine) palladium(0) / water; 1,4-dioxane / 3 h / 110 °C / Microwave irradiation
6.1: lithium hydroxide monohydrate; water / tetrahydrofuran; ethanol / 2 h / 100 °C / Inert atmosphere
7.1: periodic acid; chromium(VI) oxide / acetonitrile; water / 1.5 h / 0 - 23 °C
8.1: copper(ll) bromide; tert.-butylnitrite / acetonitrile / 0.5 h / 20 °C
9.1: potassium carbonate; tetrakis(triphenylphosphine) palladium(0) / water; 1,4-dioxane / 1 h / 100 °C / Inert atmosphere
10.1: water; sodium hydroxide / tetrahydrofuran; ethanol / 50 °C
With
pyridine; chromium(VI) oxide; tetrakis(triphenylphosphine) palladium(0); tert.-butylnitrite; perchloric acid; lithium hydroxide monohydrate; platinum on activated charcoal; water; hydrogen; potassium carbonate; acetic acid; periodic acid; sodium hydroxide; copper(ll) bromide;
In
tetrahydrofuran; 1,4-dioxane; ethanol; dichloromethane; water; acetonitrile;