3-(2-PHENOXYPHENYL)ACRYLIC ACID

Base Information

• Chemical Name: 3-(2-PHENOXYPHENYL)ACRYLIC ACID
• CAS No.: 95433-16-2
• Molecular Formula: C15H12 O3
• Molecular Weight: 240.258
• Hs Code.: 2918990090
• Mol file: 95433-16-2.mol

Synonyms:2-Phenoxycinnamicacid

Chemical Property of 3-(2-PHENOXYPHENYL)ACRYLIC ACID

Chemical Property:

• Vapor Pressure: 1.03E-06mmHg at 25°C
• Melting Point: 182-184°C
• Refractive Index: 1.636
• Boiling Point: 387.9°Cat760mmHg
• Flash Point: 145.8°C
• PSA: 46.53000
• Density: 1.228g/cm³
• LogP: 3.57670

Purity/Quality:

98%min ^*data from raw suppliers

3-(2-Phenoxyphenyl)acrylic acid >95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-(2-PHENOXYPHENYL)ACRYLIC ACID

There total 4 articles about 3-(2-PHENOXYPHENYL)ACRYLIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

malonic acid (141-82-2) + 2-(phenoxy)benzaldehyde (19434-34-5) → (E)-3-(2-phenoxyphenyl)acrylic acid (95433-16-2)

Guidance literature:

With piperidine; pyridine; at 120 ℃; for 3h;

DOI:10.1016/j.ejmech.2019.111723

Reference yield:

bromobenzene (108-86-1,52753-63-6) → (E)-3-(2-phenoxyphenyl)acrylic acid (95433-16-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 200 - 210 °C

2: pyridine; piperidine

With piperidine; pyridine;

DOI:10.1021/ja01166a128

Reference yield:

iodobenzene (591-50-4) → (E)-3-(2-phenoxyphenyl)acrylic acid (95433-16-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 200 - 210 °C

2: pyridine; piperidine

With piperidine; pyridine;

DOI:10.1021/ja01166a128

upstream raw materials:

malonic acid

2-(phenoxy)benzaldehyde

bromobenzene

iodobenzene

Downstream raw materials:

(E)-N-hydroxy-3-(2-phenoxyphenyl)acrylamide

Refernces