6-Chloro-o-acetacetotoluidide

Base Information

• Chemical Name: 6-Chloro-o-acetacetotoluidide
• CAS No.: 91089-62-2
• Molecular Formula: C11H12ClNO2
• Molecular Weight: 225.67
• Hs Code.: 2924299090
• Mol file: 91089-62-2.mol

Synonyms:o-Acetoacetotoluidide,6'-chloro- (7CI);

Chemical Property of 6-Chloro-o-acetacetotoluidide

Chemical Property:

• Vapor Pressure: 4.68E-06mmHg at 25°C
• Refractive Index: 1.572
• Boiling Point: 382.6 °C at 760 mmHg
• Flash Point: 185.2 °C
• PSA: 46.17000
• Density: 1.247 g/cm³
• LogP: 2.63900

Purity/Quality:

98%min ^*data from raw suppliers

N-(2-Chloro-6-methylphenyl)-3-oxobutanamide 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-Chloro-o-acetacetotoluidide

There total 2 articles about 6-Chloro-o-acetacetotoluidide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl acetoacetate (141-97-9) + 2-chloro-6-methylaniline (87-63-8) → acetoacetic acid-(2-chloro-6-methyl-anilide) (91089-62-2)

Guidance literature:

With chlorobenzene;

Reference yield:

4-methyleneoxetan-2-one (674-82-8,2130-41-8) + 2-chloro-6-methylaniline (87-63-8) → acetoacetic acid-(2-chloro-6-methyl-anilide) (91089-62-2)

Guidance literature:

DOI:10.1246/bcsj.36.492

Reference yield: 45.0%

acetoacetic acid-(2-chloro-6-methyl-anilide) (91089-62-2) + N,N-Dimethylhydrazine (57-14-7) → N-(2-Chloro-6-methylphenyl)-2,6-dimethyl-4-oxo-4H-pyran-3-carboxamide

Guidance literature:

upstream raw materials:

ethyl acetoacetate

2-chloro-6-methylaniline

4-methyleneoxetan-2-one

Downstream raw materials:

(2-Hydroxy-5-sulfamoyl-phenylazo)-2-chlor-6-methyl-acetoacetanilid