4-(N-ethoxycarbonylaminomethyl)-N-ethoxycarbonylaniline

Base Information

• Chemical Name: 4-(N-ethoxycarbonylaminomethyl)-N-ethoxycarbonylaniline
• CAS No.: 77586-27-7
• Molecular Formula: C₁₃H₁₈N₂O₄
• Molecular Weight: 266.297
• Mol file: 77586-27-7.mol

Synonyms:4-(N-ethoxycarbonylaminomethyl)-N-ethoxycarbonylaniline

Chemical Property of 4-(N-ethoxycarbonylaminomethyl)-N-ethoxycarbonylaniline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(N-ethoxycarbonylaminomethyl)-N-ethoxycarbonylaniline

There total 2 articles about 4-(N-ethoxycarbonylaminomethyl)-N-ethoxycarbonylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

N,N'-methanediyl-bis-carbamic acid diethyl ester (3693-53-6) + N-carboethoxyaniline (101-99-5) → (methylenedi-4,1-phenylene)bis-carbamic acid diethyl ester (10097-16-2) + 4-(N-ethoxycarbonylaminomethyl)-N-ethoxycarbonylaniline (77586-27-7)

Guidance literature:

With boron trifluoride diethyl etherate; In benzene; for 24h; Heating;

DOI:10.1039/P19810000447

Reference yield: 22.0%

N,N'-methanediyl-bis-carbamic acid diethyl ester (3693-53-6) + N-ethoxycarbonylazepine (2955-79-5) → N-carboethoxyaniline (101-99-5) + (methylenedi-4,1-phenylene)bis-carbamic acid diethyl ester (10097-16-2) + 4-(N-ethoxycarbonylaminomethyl)-N-ethoxycarbonylaniline (77586-27-7)

Guidance literature:

With boron trifluoride diethyl etherate; In benzene; for 24h; Mechanism; Heating; intermediate formation of N-ethoxycarbonylmethyleneamine (NEM, CH₂=NCO₂Et);

DOI:10.1039/P19810000447

Reference yield: 94.0%

N-carboethoxyaniline (101-99-5) + 4-(N-ethoxycarbonylaminomethyl)-N-ethoxycarbonylaniline (77586-27-7) → (methylenedi-4,1-phenylene)bis-carbamic acid diethyl ester (10097-16-2)

Guidance literature:

With boron trifluoride diethyl etherate; In benzene; for 24h; Heating;

DOI:10.1039/P19810000447

upstream raw materials:

N,N'-methanediyl-bis-carbamic acid diethyl ester

N-carboethoxyaniline

N-ethoxycarbonylazepine

Downstream raw materials:

(methylenedi-4,1-phenylene)bis-carbamic acid diethyl ester

[4-(Ethoxycarbonylamino-methyl)-cyclohexyl]-carbamic acid ethyl ester

dicyclohexylmethane-4,4'-diethylurethane

Refernces