C₄₄H₅₃NO₃SSi₂

Base Information

• Chemical Name: C₄₄H₅₃NO₃SSi₂
• CAS No.: 1379039-08-3
• Molecular Formula: C₄₄H₅₃NO₃SSi₂
• Molecular Weight: 732.147
• Mol file: 1379039-08-3.mol

Synonyms:C₄₄H₅₃NO₃SSi₂

Chemical Property of C₄₄H₅₃NO₃SSi₂

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of C₄₄H₅₃NO₃SSi₂

There total 3 articles about C₄₄H₅₃NO₃SSi₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-p-toluenesulfonyl-4(R)-amino-5-tert-butyldiphenylsilyl-1-tert-butyldiphenylsilyloxy-2(S)-pentanol (1379039-05-0) → C44H53NO3SSi2 (1379039-08-3)

Guidance literature:

With di-isopropyl azodicarboxylate; triphenylphosphine; In benzene; at 0 - 25 ℃; for 1h;

DOI:10.1039/c2ob07140a

Reference yield:

tert-butylchlorodiphenylsilane (58479-61-1) → C44H53NO3SSi2 (1379039-08-3)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 1H-imidazole / dichloromethane / 0.08 h / 0 °C

1.2: 4 h / 0 - 25 °C

2.1: di-isopropyl azodicarboxylate; triphenylphosphine / benzene / 1 h / 0 - 25 °C

With 1H-imidazole; di-isopropyl azodicarboxylate; triphenylphosphine; In dichloromethane; benzene; 2.1: Mitsunobu reaction;

DOI:10.1039/c2ob07140a

Reference yield:

C28H37NO4SSi → C44H53NO3SSi2 (1379039-08-3)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 1H-imidazole / dichloromethane / 0.08 h / 0 °C

1.2: 4 h / 0 - 25 °C

2.1: di-isopropyl azodicarboxylate; triphenylphosphine / benzene / 1 h / 0 - 25 °C

With 1H-imidazole; di-isopropyl azodicarboxylate; triphenylphosphine; In dichloromethane; benzene; 2.1: Mitsunobu reaction;

DOI:10.1039/c2ob07140a

upstream raw materials:

N-p-toluenesulfonyl-4(R)-amino-5-tert-butyldiphenylsilyl-1-tert-butyldiphenylsilyloxy-2(S)-pentanol

tert-butylchlorodiphenylsilane

Downstream raw materials:

(2S,4R)-2-Hydroxymethyl-4-hydroxy-1-(4-toluenesulfonyl)-pyrrolidine

Refernces