Dimethylmethoxy(4-methylphenyl)silane

Base Information

• Chemical Name: Dimethylmethoxy(4-methylphenyl)silane
• CAS No.: 51501-87-2
• Molecular Formula: C10H16OSi
• Molecular Weight: 180.322
• Hs Code.: 2931900090
• DSSTox Substance ID: DTXSID80199486
• Wikidata: Q83072406
• Mol file: 51501-87-2.mol

Synonyms:51501-87-2;Methoxydimethyl(p-tolyl)silane;DIMETHYLMETHOXY(4-METHYLPHENYL)SILANE;methoxy-dimethyl-(4-methylphenyl)silane;Silane, methoxydimethyl(4-methylphenyl)-;Silane,methoxydimethyl(4-methylphenyl)-;SCHEMBL3482430;DTXSID80199486;MFCD09266166;CS-0453178;A924270

Chemical Property of Dimethylmethoxy(4-methylphenyl)silane

Chemical Property:

• Vapor Pressure: 0.314mmHg at 25°C
• Refractive Index: 1.476
• Boiling Point: 208 °C at 760 mmHg
• Flash Point: 72.4 °C
• PSA: 9.23000
• Density: 0.91 g/cm³
• LogP: 2.05350
• Sensitive.: Moisture Sensitive
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 180.097041664
• Heavy Atom Count: 12
• Complexity: 137

Purity/Quality:

98%Min ^*data from raw suppliers

Methoxydimethyl(P-Tolyl)Silane ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)[Si](C)(C)OC

Technology Process of Dimethylmethoxy(4-methylphenyl)silane

There total 6 articles about Dimethylmethoxy(4-methylphenyl)silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

methanol (67-56-1) + dimethyl-p-tolylsilane (1432-39-9) → dimethyl(4-methylphenyl)methoxysilane (51501-87-2)

Guidance literature:

With (p-cymene)ruthenium(II) chloride; at 20 ℃; for 0.0833333h;

DOI:10.1021/jo301363h

Reference yield:

para-bromotoluene (106-38-7) → dimethyl(4-methylphenyl)methoxysilane (51501-87-2)

Guidance literature:

Multi-step reaction with 2 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 2 h / -78 °C / Inert atmosphere

1.2: -78 - 20 °C / Inert atmosphere

2.1: (p-cymene)ruthenium(II) chloride / 0.08 h / 20 °C

With n-butyllithium; (p-cymene)ruthenium(II) chloride; In tetrahydrofuran; hexane;

DOI:10.1021/jo301363h

Reference yield:

methanol (67-56-1) + (4-methylphenyl)dimethylsilanol (17920-15-9) → dimethyl(4-methylphenyl)methoxysilane (51501-87-2)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; at 25 ℃; for 1h; Rate constant; Equilibrium constant; var. of reagent;

DOI:10.1002/prac.199633801125

upstream raw materials:

methanol

para-bromotoluene

dimethylmethoxychlorosilane

(4-methylphenyl)dimethylsilanol

Downstream raw materials:

p-cresol

methanol

(4-methylphenyl)dimethylsilanol

Refernces

• 1、 Kohlheim,Lange,Kelling. "On the reaction of silanols with alcohols". . p. 660 - 662. Retrieved 2007/10/03.
• 2、 Lapkin, I. I.,Mukhina, R. G.,Kirillov, N. F.. "CHEMICAL ACTIVITY AND STERIC ACCESSIBILITY. XVIII. REACTION OF ALKOXYCHLOROSILANES WITH ORGANOMAGNESIUM COMPOUNDS". . p. 125 - 129. Retrieved 2007/10/02.