4,5-dibromo-2-benzoylthiophene

Base Information

• Chemical Name: 4,5-dibromo-2-benzoylthiophene
• CAS No.: 31161-45-2
• Molecular Formula: C₁₁H₆Br₂OS
• Molecular Weight: 346.042
• Mol file: 31161-45-2.mol

Synonyms:4,5-dibromo-2-benzoylthiophene

Chemical Property of 4,5-dibromo-2-benzoylthiophene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,5-dibromo-2-benzoylthiophene

There total 6 articles about 4,5-dibromo-2-benzoylthiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

2,3-dibromothiophen (3140-93-0) + benzoyl chloride (98-88-4) → 4,5-dibromo-2-benzoylthiophene (31161-45-2)

Guidance literature:

With aluminum (III) chloride; In dichloromethane; for 24h; Cooling with ice;

DOI:10.1016/j.electacta.2020.137677

Reference yield:

→ 4,5-dibromo-2-benzoylthiophene (31161-45-2)

Guidance literature:

With water; bromine; potassium bromide;

DOI:10.1021/ja01291a065

Reference yield:

2-Benzoylthiophene (135-00-2) → 4,5-dibromo-2-benzoylthiophene (31161-45-2)

Guidance literature:

With bromine;

upstream raw materials:

2,3-dibromothiophen

benzoyl chloride

2-Benzoylthiophene

water

Downstream raw materials:

Tetrabromothiophene

(4-bromothiophen-2-yl)(phenyl)methanone

2-Benzoylthiophene

3-nitrobenzoic acid

Refernces