DIMETHYL PHTHALATE (RING-D4)

Base Information

• Chemical Name: DIMETHYL PHTHALATE (RING-D4)
• CAS No.: 93951-89-4
• Molecular Formula: C10H6 D4 O4
• Molecular Weight: 198.21
• Mol file: 93951-89-4.mol

Synonyms:1,2-Benzene-3,4,5,6-d4-dicarboxylicacid, dimethyl ester (9CI)

Chemical Property of DIMETHYL PHTHALATE (RING-D4)

Chemical Property:

• Melting Point: 2 °C(lit.)
• Refractive Index: n20/D 1.515(lit.)
• Boiling Point: 282 °C(lit.)
• Flash Point: 295 °F
• PSA: 52.60000
• Density: 1.214 g/mL at 25 °C
• LogP: 1.25980
• Storage Temp.: Room Temperature, under inert atmosphere
• Solubility.: Chloroform (Slightly), Methanol (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

Dimethyl phthalate-3,4,5,6-d4 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of DIMETHYL PHTHALATE (RING-D4)

There total 3 articles about DIMETHYL PHTHALATE (RING-D4) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.7%

methanol (67-56-1) + 3,4,5,6-tetradeuterophtaloyl dicarboxylic acid (87976-26-9) → dimethyl phthalate-3,4,5,6-d4 (93951-89-4)

Guidance literature:

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 1h;

DOI:10.1002/jlcr.3930

Reference yield:

o-xylene-d10 (56004-61-6) → dimethyl phthalate-3,4,5,6-d4 (93951-89-4)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium permanganate; water / 2-methyl-propan-1-ol / 20 °C / Reflux

2: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 1 h / 20 °C

With dmap; potassium permanganate; water; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; 2-methyl-propan-1-ol;

DOI:10.1002/jlcr.3930

Reference yield:

→ dimethyl phthalate-3,4,5,6-d4 (93951-89-4)

Guidance literature:

Silber-tetradeuterio-phthalat, Methyliodid, A.;

DOI:10.1139/v63-349

upstream raw materials:

o-xylene-d10

methanol

3,4,5,6-tetradeuterophtaloyl dicarboxylic acid

Refernces