5-Methoxy-4,7-phenanthroline

Base Information

• Chemical Name: 5-Methoxy-4,7-phenanthroline
• CAS No.: 951-06-4
• Molecular Formula: C13H10 N2 O
• Molecular Weight: 210.235
• Hs Code.: 2933990090
• NSC Number: 142220
• DSSTox Substance ID: DTXSID90301290
• Nikkaji Number: J880.822H
• Wikidata: Q82045024
• Mol file: 951-06-4.mol

Synonyms:5-methoxy-4,7-phenanthroline;951-06-4;NSC142220;SCHEMBL9271551;DTXSID90301290;MATJLKZMEUUKEN-UHFFFAOYSA-N;NSC-142220;CS-0257024;EN300-658574;Z2050118569

Chemical Property of 5-Methoxy-4,7-phenanthroline

Chemical Property:

• Vapor Pressure: 2.82E-06mmHg at 25°C
• Melting Point: 105 °C
• Refractive Index: 1.697
• Boiling Point: 401°C at 760 mmHg
• PKA: 4.67±0.40(Predicted)
• Flash Point: 133.9°C
• PSA: 35.01000
• Density: 1.25g/cm³
• LogP: 2.79160
• XLogP3: 2.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 210.079312947
• Heavy Atom Count: 16
• Complexity: 246

Purity/Quality:

99%+, ^*data from raw suppliers

5-METHOXY-4,7-PHENANTHROLINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C2C(=C3C=CC=NC3=C1)C=CC=N2

Technology Process of 5-Methoxy-4,7-phenanthroline

There total 8 articles about 5-Methoxy-4,7-phenanthroline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

glycerol (56-81-5,25618-55-7,64333-26-2,8013-25-0) + 2-methoxy-1,4-phenylenediamine sulfate (66671-82-7) → 5-methoxy-[4,7]phenanthroline (951-06-4)

Guidance literature:

With sulfuric acid; sodium 3-nitrobenzenesulfonate; In water; for 6h; Heating;

DOI:10.1080/00397919608003579

Reference yield:

2-methoxy-1,4-phenylenediamine (5307-02-8) → 5-methoxy-[4,7]phenanthroline (951-06-4)

Guidance literature:

With arsenic(V) oxide; sulfuric acid; glycerol;

Reference yield:

5-chloro-4,7-phenanthroline (78941-92-1) → 5-methoxy-[4,7]phenanthroline (951-06-4)

Guidance literature:

With potassium hydroxide; copper; at 180 ℃;

upstream raw materials:

6-amino-8-methoxyquinoline

sodium 3-nitrobenzenesulfonate

5-chloro-4,7-phenanthroline

2-methoxy-1,4-phenylenediamine

Downstream raw materials:

4,7-phenanthrolino-5,6:5’,6'-pyrazine

phanquinone

Refernces

• 1、 Imor, Susan,Morgan, Robert J.,Wang, Sihe,Morgan, Oma,Baker. "An improved preparation of 4,7-phenanthrolino-5,6:5′,6′-pyrazine". . p. 2197 - 2203. Retrieved 2007/10/03.