6-METHOXYBENZOTHIAZOLE-2-CARBOXAMIDE

Base Information

• Chemical Name: 6-METHOXYBENZOTHIAZOLE-2-CARBOXAMIDE
• CAS No.: 946-12-3
• Molecular Formula: C9H8 N2 O2 S
• Molecular Weight: 208.241
• Hs Code.: 2934200090
• Mol file: 946-12-3.mol

Synonyms:2-Carbamoyl-6-methoxybenzothiazole;6-Methoxybenzothiazole-2-carboxamide

Chemical Property of 6-METHOXYBENZOTHIAZOLE-2-CARBOXAMIDE

Chemical Property:

• Vapor Pressure: 1.84E-06mmHg at 25°C
• Refractive Index: 1.678
• Boiling Point: 395.5°Cat760mmHg
• Flash Point: 193°C
• PSA: 93.45000
• Density: 1.397g/cm³
• LogP: 2.10410
• Storage Temp.: 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

6-Methoxybenzo[d]thiazole-2-carboxamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-METHOXYBENZOTHIAZOLE-2-CARBOXAMIDE

There total 2 articles about 6-METHOXYBENZOTHIAZOLE-2-CARBOXAMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

2-(4-methoxyphenylamino)-2-thioxoacetamide (71369-81-8) → 1-Thio-oxalsaeure-1-<4-methoxy-anilid> (946-61-2) + 6-methoxybenzothiazole-2-carboxamide (946-12-3)

Guidance literature:

With sodium hydroxide; potassium hexacyanoferrate(III); In water;

DOI:10.1023/A:1015082318393

Reference yield: 65.0%

2-(4-methoxyphenylamino)-2-thioxoacetamide (71369-81-8) → 6-methoxybenzothiazole-2-carboxamide (946-12-3)

Guidance literature:

With sodium hydroxide; potassium hexacyanoferrate(III); In water; for 1h;

DOI:10.1080/17415993.2011.641558

Reference yield: 80.0%

6-methoxybenzothiazole-2-carboxamide (946-12-3) → 6-methoxybenzo[d]thiazol-2-carboxylic acid (946-13-4)

Guidance literature:

With sodium hydroxide; for 0.75h; Heating;

DOI:10.1023/A:1015383007839

upstream raw materials:

2-(4-methoxyphenylamino)-2-thioxoacetamide

Downstream raw materials:

6-hydroxybenzothiazole

6-methoxybenzo[d]thiazol-2-carboxylic acid

6-methoxy-benzothiazole-2-carboxylic acid methyl ester

6-methoxybenzothiazole-2-carboxylic acid hydrazide

Refernces

• 1、 Yarovenko, V. N.,Stoyanovich, F. M.,Zolotarskaya, O. Yu.,Chernoburova, E. I.,Zararzin, I. V.,Krayushkin, M. M.. "New approach to the synthesis of 2-carbamoylbenzothiazoles". . p. 144 - 147. Retrieved 2007/10/03.