3,5-DINITROPYRIDINE

Base Information

• Chemical Name: 3,5-DINITROPYRIDINE
• CAS No.: 940-06-7
• Molecular Formula: C5H3 N3 O4
• Molecular Weight: 169.097
• Hs Code.: 2933399090
• Mol file: 940-06-7.mol

Synonyms:3,5-Dinitropyridine

Chemical Property of 3,5-DINITROPYRIDINE

Chemical Property:

• Vapor Pressure: 0.00445mmHg at 25°C
• Melting Point: 145-146 °C
• Refractive Index: 1.621
• Boiling Point: 286.8oC at 760 mmHg
• PKA: -2.84±0.20(Predicted)
• Flash Point: 127.3oC
• PSA: 104.53000
• Density: 1.59g/cm3
• LogP: 1.94440
• Storage Temp.: Refrigerator
• Solubility.: Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slig

Purity/Quality:

98%min ^*data from raw suppliers

3,5-Dinitropyridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 3,5-Dinitropyridine is used as an azabenzyne pyrolytic precursor. The anion radical of 3,5-dinitropyridine aundergoes reversible dimerization reactions.

Technology Process of 3,5-DINITROPYRIDINE

There total 12 articles about 3,5-DINITROPYRIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

benzaldehyde (100-52-7) + N-tert-butyl-β-formyl-β-nitroenamine (181294-58-6) → 3,5-dinitropyridine (940-06-7) + 1-(tert-butyl)-1,4-dihydro-3,5-dinitro-4-phenylpyridine

Guidance literature:

With toluene-4-sulfonic acid; In ethanol; at 80 ℃; for 20h;

DOI:10.1039/c5ra19439c

Reference yield: 81.0%

4-chlorobenzaldehyde (104-88-1) + N-tert-butyl-β-formyl-β-nitroenamine (181294-58-6) → 3,5-dinitropyridine (940-06-7) + 1-(tert-butyl)-4-(4-chlorophenyl)-1,4-dihydro-3,5-dinitropyridine

Guidance literature:

With toluene-4-sulfonic acid; In ethanol; at 80 ℃; for 20h;

DOI:10.1039/c5ra19439c

Reference yield: 75.0%

4-nitrobenzaldehdye (555-16-8) + N-tert-butyl-β-formyl-β-nitroenamine (181294-58-6) → 3,5-dinitropyridine (940-06-7) + 1-(tert-butyl)-1,4-dihydro-3,5-dinitro-4-(4-nitrophenyl)pyridine

Guidance literature:

With toluene-4-sulfonic acid; In ethanol; at 80 ℃; for 20h;

DOI:10.1039/c5ra19439c

upstream raw materials:

4-methoxy-benzaldehyde

N-tert-butyl-β-formyl-β-nitroenamine

4-methyl-benzaldehyde

benzaldehyde

Refernces

• 1、 Asahara, Haruyasu,Hamada, Mai,Nakaike, Yumi,Nishiwaki, Nagatoshi. "Construction of 3,5-dinitrated 1,4-dihydropyridines modifiable at 1,4-positions by a reaction of β-formyl-β-nitroenamines with aldehydes". . p. 90778 - 90784. Retrieved 2015/11/10.