2,4,6-Cycloheptatrien-1-one, 2-bromo-

Base Information

• Chemical Name: 2,4,6-Cycloheptatrien-1-one, 2-bromo-
• CAS No.: 932-55-8
• Molecular Formula: C7H5 Br O
• Molecular Weight: 185.02
• Mol file: 932-55-8.mol

Synonyms:2-Bromocycloheptatrienone;2-Bromotropone

Chemical Property of 2,4,6-Cycloheptatrien-1-one, 2-bromo-

Chemical Property:

• Melting Point: 60-63 °C
• PSA: 17.07000
• LogP: 1.80930

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 22-34-42/43
• Safety Statements: 23-26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,4,6-Cycloheptatrien-1-one, 2-bromo-

There total 5 articles about 2,4,6-Cycloheptatrien-1-one, 2-bromo- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

2-(tosyloxy)tropone (38768-08-0) → 2-bromotropone (932-55-8)

Guidance literature:

With 1-butyl-3-methylimidazolium Tetrafluoroborate; lithium bromide; at 80 ℃; for 0.5h;

DOI:10.1016/j.tetlet.2004.03.050

Reference yield: 32.0%

7-oxocyclohepta-1,3,5-trien-1-yl benzenesulfonate (35270-65-6) → 2-bromotropone (932-55-8)

Guidance literature:

With boron trifluoride diethyl etherate; lithium bromide; In methanol; for 1.5h; Heating;

DOI:10.1080/00397919708005641

Reference yield:

2-chlorotropone (3839-48-3) → 2-bromotropone (932-55-8)

Guidance literature:

With hydrogen bromide; acetic acid;

DOI:10.1021/ja01142a039

upstream raw materials:

2-chlorotropone

2-hydrazinotropone

7-oxocyclohepta-1,3,5-trien-1-yl benzenesulfonate

2-(tosyloxy)tropone

Downstream raw materials:

2-benzyltropone

cycloheptapyrrole

Triphenylphosphine oxide

2-phenyl-1-azaazulene

Refernces

• 1、 Cavazza, Marino,Pietra, Francesco. "A general entry to 10-halocolchicides and 9-haloisocolchicides". . p. 3405 - 3413. Retrieved 2007/10/03.