2-chlorophenyl nonaflate

Base Information

• Chemical Name: 2-chlorophenyl nonaflate
• CAS No.: 147641-13-2
• Molecular Formula: C₁₀H₄ClF₉O₃S
• Molecular Weight: 410.645
• Mol file: 147641-13-2.mol

Synonyms:2-chlorophenyl nonaflate

Chemical Property of 2-chlorophenyl nonaflate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-chlorophenyl nonaflate

There total 1 articles about 2-chlorophenyl nonaflate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

Nonafluorobutanesulfonyl fluoride (375-72-4) + 2-monochlorophenol (95-57-8) → 2-chlorophenyl nonaflate (147641-13-2)

Guidance literature:

With dmap; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 12h;

DOI:10.1021/jo034962a

Reference yield: 93.0%

aniline (62-53-3) + 2-chlorophenyl nonaflate (147641-13-2) → N-phenyl-2-chloroaniline (1205-40-9)

Guidance literature:

With tris(dibenzylideneacetone)dipalladium ⁽⁰⁾; 1-methyl-2,3,4,6,7,8-hexahydro-1H-pyrimido[1,2-a]pyrimidine; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In toluene; at 150 ℃; for 0.5h; microwave irradiation;

DOI:10.1021/jo052131u

Reference yield: 92.0%

phenyl(1-phenylethylidene)amine (1749-19-5) + 2-chlorophenyl nonaflate (147641-13-2) → 1,2-diphenyl-1H-indole (18434-12-3)

Guidance literature:

With tris(dibenzylideneacetone)dipalladium ⁽⁰⁾; lithium tert-butoxide; XPhos; In 1,4-dioxane; at 110 ℃; Inert atmosphere;

upstream raw materials:

Nonafluorobutanesulfonyl fluoride

2-monochlorophenol

Downstream raw materials:

4-(2-chlorophenyl)morpholine

N-(2-chlorophenyl)-n-hexylamine

N-phenyl-2-chloroaniline

1,2-diphenyl-1H-indole

Refernces

• 1、 Barluenga, Jose,Jimenez-Aquino, Agustin,Aznar, Fernando,Valdes, Carlos. "Modular synthesis of indoles from imines and o-dihaloarenes or o-chlorosulfonates by a Pd-catalyzed cascade process". supporting information; experimental part. p. 4031 - 4041. Retrieved 2009/09/04.