2-CHLORO-4,5,7,8-TETRAHYDRO-6H-THIENO[2,3-D]AZEPINE-6-CARBOXYLIC ACID, T-BUTYLESTER

Base Information Edit

Chemical Name:2-CHLORO-4,5,7,8-TETRAHYDRO-6H-THIENO[2,3-D]AZEPINE-6-CARBOXYLIC ACID, T-BUTYLESTER
CAS No.:873016-30-9
Molecular Formula:C11H15 N O2 S
Molecular Weight:225.31
Hs Code.:
Mol file:873016-30-9.mol

Synonyms:2-CHLORO-4,5,7,8-TETRAHYDRO-6H-THIENO[2,3-D]AZEPINE-6-CARBOXYLIC ACID, T-BUTYLESTER

Suppliers and Price of 2-CHLORO-4,5,7,8-TETRAHYDRO-6H-THIENO[2,3-D]AZEPINE-6-CARBOXYLIC ACID, T-BUTYLESTER

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-CHLORO-4,5,7,8-TETRAHYDRO-6H-THIENO-[2,3-D]AZEPINE-6-CARBOXYLIC ACID-TERT-BUTYL ESTER 95.00%
5MG
$ 497.18

Total 1 raw suppliers

Chemical Property of 2-CHLORO-4,5,7,8-TETRAHYDRO-6H-THIENO[2,3-D]AZEPINE-6-CARBOXYLIC ACID, T-BUTYLESTER Edit

Chemical Property:

PSA：57.78000
LogP:3.67510

Purity/Quality:

99%min ^*data from raw suppliers

2-CHLORO-4,5,7,8-TETRAHYDRO-6H-THIENO-[2,3-D]AZEPINE-6-CARBOXYLIC ACID-TERT-BUTYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-CHLORO-4,5,7,8-TETRAHYDRO-6H-THIENO[2,3-D]AZEPINE-6-CARBOXYLIC ACID, T-BUTYLESTER

There total 7 articles about 2-CHLORO-4,5,7,8-TETRAHYDRO-6H-THIENO[2,3-D]AZEPINE-6-CARBOXYLIC ACID, T-BUTYLESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 541-41-3
chloroformic acid ethyl ester

: 102997-01-3
5,6,7,8-tetrahydro-4H-thieno<2,3-d>azepine

: 873016-30-9
4,5,7,8-tetrahydro-thieno[2,3-d]azepine-6-carboxylic acid ethyl ester

Guidance literature:: In tetrahydrofuran; at 0 - 20 ℃; for 4h;

Reference yield: 62.0%

: 873016-29-6
ethyl 4-oxo-7,8-dihydro-4H-thieno[2,3-d]azepine-6(5H)-carboxylate

: 873016-30-9
4,5,7,8-tetrahydro-thieno[2,3-d]azepine-6-carboxylic acid ethyl ester

Guidance literature:: With aluminum (III) chloride; tert-butylamine; diborane; In dichloromethane; at 0 - 25 ℃; for 12h;

Reference yield:

: 30433-91-1
[2-(2-thyenyl)ethyl]amine

: 873016-30-9
4,5,7,8-tetrahydro-thieno[2,3-d]azepine-6-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 6 steps

1: sodium tris(acetoxy)borohydride; acetic acid / dichloromethane / 16 h / 15 - 25 °C

2: sodium hydrogencarbonate / tetrahydrofuran / 16 h / 0 - 25 °C

3: sodium hydroxide; water / ethanol / 16 h / 0 - 25 °C

4: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 16 h / 0 - 25 °C

5: aluminum (III) chloride / dichloromethane / 1 h / 0 - 25 °C

6: aluminum (III) chloride; tert-butylamine; diborane / dichloromethane / 12 h / 0 - 25 °C

With aluminum (III) chloride; oxalyl dichloride; water; sodium tris(acetoxy)borohydride; sodium hydrogencarbonate; acetic acid; tert-butylamine; N,N-dimethyl-formamide; sodium hydroxide; diborane; In tetrahydrofuran; ethanol; dichloromethane;