almotriptan 2-hydroxy benzoate

Base Information

• Chemical Name: almotriptan 2-hydroxy benzoate
• CAS No.: 922735-96-4
• Molecular Formula: C₇H₆O₃*C₁₇H₂₅N₃O₂S
• Molecular Weight: 473.593
• Mol file: 922735-96-4.mol

Synonyms:almotriptan 2-hydroxy benzoate

Chemical Property of almotriptan 2-hydroxy benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of almotriptan 2-hydroxy benzoate

There total 1 articles about almotriptan 2-hydroxy benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

salicylic acid (69-72-7,25496-36-0,8052-31-1) + almotriptan (154323-57-6) → almotriptan 2-hydroxy benzoate (922735-96-4)

Guidance literature:

In ethanol; at 20 ℃; for 3.5h; Heating / reflux;

Reference yield:

almotriptan 2-hydroxy benzoate (922735-96-4) + malic acid (617-48-1,78644-42-5) → almotriptan malate (181183-52-8)

Guidance literature:

almotriptan 2-hydroxy benzoate; With ammonia; In methanol; water; ethyl acetate; for 1h;

malic acid; In methanol; at 25 ℃; for 4.5h; Product distribution / selectivity; Heating / reflux;

upstream raw materials:

salicylic acid

almotriptan

Downstream raw materials:

almotriptan malate

Refernces

• 1、 -. "A PROCESS FOR THE PREPARATION OF ALMOTRIPTAN". Page/Page column 7. . Retrieved 2010/11/25.