K114

Base Information

• Chemical Name: K114
• CAS No.: 872201-12-2
• Molecular Formula: C22H17 Br O2
• Molecular Weight: 393.27
• Mol file: 872201-12-2.mol

Synonyms:K 114; K114 (fluorescing agent)

Chemical Property of K114

Chemical Property:

• PSA: 40.46000
• LogP: 6.20110
• Storage Temp.: Store at +4°C
• Solubility.: DMSO: soluble >10mg/mL

Purity/Quality:

99% ^*data from raw suppliers

K 114 ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

• Uses: K 114 is a potent amyloid fibril-specific fluorescent dye. K 114 is a potent amyloid fibril-specific fluorescent dye similar to Congo Red and BSB. K 114 recognizes amyloid lesions and facilitates quantitative monitoring of the formation of amyloid fibrils assembled from the Aβ peptide, α-synuclein, and tau. The affinity for fibrils ranges 20-30 nM. Unlike the other compounds K114 has minimal fluorescence in aqueous buffers, but fluoresces brightly in the presence of amyloid fibrils. K114 can be used to monitor in vitro amyloid fibril formation by fluorescence emission at 550 nm.