α-Methoxy-β,β-dimethylstyrol

Base Information

• Chemical Name: α-Methoxy-β,β-dimethylstyrol
• CAS No.: 50407-04-0
• Molecular Formula: C₁₁H₁₄O
• Molecular Weight: 162.232
• Mol file: 50407-04-0.mol

Synonyms:α-Methoxy-β,β-dimethylstyrol

Chemical Property of α-Methoxy-β,β-dimethylstyrol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of α-Methoxy-β,β-dimethylstyrol

There total 27 articles about α-Methoxy-β,β-dimethylstyrol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

(1,1-Dimethoxy-2-methyl-propyl)-benzene (66202-92-4) → α-Methoxy-β,β-dimethylstyrol (50407-04-0)

Guidance literature:

With pyridine; phosphoric acid;

Reference yield: 93.0%

trimethyl phosphite (512-56-1) + phenyl isopropyl ketone (611-70-1) → α-Methoxy-β,β-dimethylstyrol (50407-04-0)

Guidance literature:

With sodium hydride; In 1-methyl-pyrrolidin-2-one; at 120 ℃; for 24h;

DOI:10.1055/a-1504-8366

Reference yield: 71.0%

methanol (67-56-1) + (E)-1-((2-methyl-1-phenylprop-1-en-1-yl)diazenyl)pyrrolidine → α-Methoxy-β,β-dimethylstyrol (50407-04-0)

Guidance literature:

With trifluoroacetic acid; at 20 ℃; for 0.333333h; Inert atmosphere;

DOI:10.1021/acs.orglett.8b01214

upstream raw materials:

methyl thiobenzoate

2-diazopropane

trimethyl phosphite

2-methyl-1-phenyl-1-propanone lithium enolate

Downstream raw materials:

methyl 2-methyl-2-phenylpropionate

Refernces

• 1、 -. "Preparation of alkylated compounds using the trialkylphosphate". Paragraph 0156-0157; 0162. . Retrieved 2021/11/02.
• 2、 Cantrell, Thomas S.,Allen, Andrew C.. "Photochemical Reactions of Arenecarboxylic Acid Esters with Electron-Rich Alkenes: 2 + 2 Cycloaddition, Hydrogen Abstraction, and Cycloreversion". . p. 135 - 139. Retrieved 2007/10/02.