(-)-Wieland-Gumlich aldehyde

Base Information

• Chemical Name: (-)-Wieland-Gumlich aldehyde
• CAS No.: 724794-46-1
• Molecular Formula: C₁₉H₂₂N₂O₂
• Molecular Weight: 310.396
• Mol file: 724794-46-1.mol

Synonyms:(-)-Wieland-Gumlich aldehyde

Chemical Property of (-)-Wieland-Gumlich aldehyde

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (-)-Wieland-Gumlich aldehyde

There total 1 articles about (-)-Wieland-Gumlich aldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 18-hydroxy-2β,16β-cur-19-en-17-oate (55968-99-5) → (-)-Wieland-Gumlich aldehyde (724794-46-1) + N(1)-desacetyl 18-hydroxyisoretuline (900-98-1)

Guidance literature:

With diisobutylaluminium hydride; In dichloromethane; at -90 ℃; Title compound not separated from byproducts;

DOI:10.1021/ja00126a017

Reference yield: 69.0%

(-)-Wieland-Gumlich aldehyde (724794-46-1) + malonic acid (141-82-2) → strychnidin-10-one (57-24-9)

Guidance literature:

With sodium acetate; acetic anhydride; In acetic acid; at 120 ℃;

DOI:10.1038/nature10232

Reference yield: 49.0%

(-)-Wieland-Gumlich aldehyde (724794-46-1) → Caracurine V (630-87-5)

Guidance literature:

With Trimethylacetic acid; at 120 ℃; for 14h;

DOI:10.1021/np990500+

upstream raw materials:

methyl 18-hydroxy-2β,16β-cur-19-en-17-oate

Downstream raw materials:

Caracurine V

strychnidin-10-one

Refernces