ethyl 3-[(4-methoxybenzoyl)amino]-2-{[4-(4-methyl-1,4-diazepan-1-yl)benzoyl]amino}benzoate hydrochloride

Base Information

• Chemical Name: ethyl 3-[(4-methoxybenzoyl)amino]-2-{[4-(4-methyl-1,4-diazepan-1-yl)benzoyl]amino}benzoate hydrochloride
• CAS No.: 365462-45-9
• Molecular Formula: C₃₀H₃₄N₄O₅*ClH
• Molecular Weight: 567.085
• Mol file: 365462-45-9.mol

Synonyms:ethyl 3-[(4-methoxybenzoyl)amino]-2-{[4-(4-methyl-1,4-diazepan-1-yl)benzoyl]amino}benzoate hydrochloride

Chemical Property of ethyl 3-[(4-methoxybenzoyl)amino]-2-{[4-(4-methyl-1,4-diazepan-1-yl)benzoyl]amino}benzoate hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl 3-[(4-methoxybenzoyl)amino]-2-{[4-(4-methyl-1,4-diazepan-1-yl)benzoyl]amino}benzoate hydrochloride

There total 4 articles about ethyl 3-[(4-methoxybenzoyl)amino]-2-{[4-(4-methyl-1,4-diazepan-1-yl)benzoyl]amino}benzoate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C30H34N4O5 (765891-23-4) → ethyl 3-[(4-methoxybenzoyl)amino]-2-{[4-(4-methyl-1,4-diazepan-1-yl)benzoyl]amino}benzoate hydrochloride (365462-45-9)

Guidance literature:

With hydrogenchloride; In water;

DOI:10.1021/jm200868m

Reference yield:

ethyl 2-amino-3-[(4-methoxybenzoyl)amino]benzoate (1350454-17-9) → ethyl 3-[(4-methoxybenzoyl)amino]-2-{[4-(4-methyl-1,4-diazepan-1-yl)benzoyl]amino}benzoate hydrochloride (365462-45-9)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / 19 h / 20 °C

2: hydrogenchloride / water

With pyridine; hydrogenchloride; In water;

DOI:10.1021/jm200868m

Reference yield:

2,3-Diaminobenzoic acid,ethyl ester (37466-88-9) → ethyl 3-[(4-methoxybenzoyl)amino]-2-{[4-(4-methyl-1,4-diazepan-1-yl)benzoyl]amino}benzoate hydrochloride (365462-45-9)

Guidance literature:

Multi-step reaction with 3 steps

1: pyridine / dichloromethane / 2 h / -70 - 0 °C

2: pyridine / 19 h / 20 °C

3: hydrogenchloride / water

With pyridine; hydrogenchloride; In dichloromethane; water;

DOI:10.1021/jm200868m

upstream raw materials:

C₃₀H₃₄N₄O₅

ethyl 2-amino-3-[(4-methoxybenzoyl)amino]benzoate

2,3-Diaminobenzoic acid,ethyl ester

4-methoxy-benzoyl chloride

Downstream raw materials:

3-[(4-methoxybenzoyl)amino]-2-{[4-(4-methyl-1,4-diazepan-1-yl)benzoyl]amino}benzoic acid hydrochloride

Refernces