C₃₉H₇₂O₃Si₂

Base Information

• Chemical Name: C₃₉H₇₂O₃Si₂
• CAS No.: 1192803-39-6
• Molecular Formula: C₃₉H₇₂O₃Si₂
• Molecular Weight: 645.17
• Mol file: 1192803-39-6.mol

Synonyms:C₃₉H₇₂O₃Si₂

Chemical Property of C₃₉H₇₂O₃Si₂

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₉H₇₂O₃Si₂

There total 11 articles about C₃₉H₇₂O₃Si₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

C45H78O6SSi2 (1402710-06-8) → C39H72O3Si2 (1192803-39-6)

Guidance literature:

With disodium hydrogenphosphate; sodium amalgam; In methanol; at 20 ℃; for 2h;

DOI:10.1016/j.steroids.2013.06.001

Reference yield:

(7aR)-7a-methyl-1-((S)-1'-(phenylsulfonyl)propane-2'-yl)hexahydro-1H-inden-4(2H)-on (1263286-71-0) → C39H72O3Si2 (1192803-39-6)

Guidance literature:

Multi-step reaction with 3 steps

1.1: n-butyllithium / tetrahydrofuran / 2 h / -60 - -40 °C

2.1: n-butyllithium; diisopropylamine / tetrahydrofuran; hexane / 0.25 h / -60 °C

2.2: 1 h / -60 °C

3.1: disodium hydrogenphosphate; sodium amalgam / methanol / 2 h / 20 °C

With disodium hydrogenphosphate; sodium amalgam; n-butyllithium; diisopropylamine; In tetrahydrofuran; methanol; hexane; 1.1: |Wittig-Horner Reaction;

DOI:10.1016/j.steroids.2013.06.001

Reference yield:

C20H41IO2Si2 (1402710-05-7) → C39H72O3Si2 (1192803-39-6)

Guidance literature:

Multi-step reaction with 4 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / 0 °C

1.2: 1 h / 0 °C

2.1: n-butyllithium / tetrahydrofuran / 2 h / -60 - -40 °C

3.1: n-butyllithium; diisopropylamine / tetrahydrofuran; hexane / 0.25 h / -60 °C

3.2: 1 h / -60 °C

4.1: disodium hydrogenphosphate; sodium amalgam / methanol / 2 h / 20 °C

With disodium hydrogenphosphate; sodium amalgam; n-butyllithium; diisopropylamine; In tetrahydrofuran; methanol; hexane; 2.1: |Wittig-Horner Reaction;

DOI:10.1016/j.steroids.2013.06.001

upstream raw materials:

(7aR)-7a-methyl-1-((S)-1'-(phenylsulfonyl)propane-2'-yl)hexahydro-1H-inden-4(2H)-on

C₂₀H₄₁IO₂Si₂

(1R,3R)-1,3-bis((tert-butyldimethyl)silanyloxy)-5-[2-(diphenylphosphinoyl)-ethylidene]cyclohexane

(R)-3-hydroxy-2,3-dimethylbutanal

Downstream raw materials:

paricalcitol

Refernces